Our body handles tissue damage by activating the immune system in response to
intracellular molecules released by injured tissues [damage-associated molecular patterns …

When cells undergo necrotic cell death in either physiological or pathophysiological settings
in vivo, they release highly immunogenic intracellular molecules and organelles into the …

Purpose This review aimed to take stock of the current status of research on damage-
associated molecular pattern (DAMP) protein. We discuss the Janus-faced role of DAMP …

Abstract P2Y receptors are G protein‐coupled receptors (GPCRs) that are activated by
adenine and uridine nucleotides and nucleotide sugars. There are eight subtypes of P2Y …

Thoracic aortic dissection (TAD) is a highly lethal vascular disease. In many patients with
TAD, the aorta progressively dilates and ultimately ruptures. Dissection formation …

Filamins are large actin-binding proteins that stabilize delicate three-dimensional actin
filament networks and link them to cellular membranes where they integrate cell …

Filamin A (FLNA) is a large actin-binding cytoskeletal protein that is important for cell motility
by stabilizing actin networks and integrating them with cell membranes. Interestingly, a C …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by a progressive
loss of memory and cognitive ability and is a serious cause of mortality. Many of the …

Aims Extracellular nucleotides are vasoactive molecules. The concentrations of these
molecules are regulated by ectonucleotidases. In this study, we investigated the role of the …

The directional movement of cells can be regulated by ATP, certain other nucleotides (eg,
ADP, UTP), and adenosine. Such regulation occurs for cells that are “professional …