Branched-chain amino acid (BCAA) catabolism has been considered to have an emerging
role in the pathogenesis of metabolic disturbances in obesity and type 2 diabetes (T2D) …

Diabetes is characterized by altered metabolism of key molecules and regulatory pathways.
The phenotypic expression of diabetes and associated complications encompasses …

Branched-chain amino acids (BCAA) have increasingly been studied as playing a role in
diabetes, with the PubMed search string" diabetes" AND" branched chain amino acids" …

The genome of pancreatic ductal adenocarcinoma (PDAC) frequently contains deletions of
tumour suppressor gene loci, most notably SMAD4, which is homozygously deleted in …

Recent studies revealed strong evidence that branched-chain and aromatic amino acids
(BCAAs and AAAs) are closely associated with the risk of developing type 2 diabetes in …

Presently, routine screening misses many cases of prediabetes and early type 2 diabetes
(T2D). Therefore, better biomarkers are needed for a simple and early detection of …

Branch chain amino acids (BCAAs) have unique properties with diverse physiological and
metabolic roles. They have functions other than simple nutrition. Different diseases including …

Beyond their contribution as fundamental building blocks of life, branched‐chain amino
acids (BCAAs) play a critical role in physiologic and pathologic processes. Importantly …

Lung cancer is the most common cause of cancer death in China. We characterized
metabolic alterations in lung cancer using two analytical platforms: a non-targeted metabolic …

LAT1 is a member of the system L transporter family. The main role of the LAT1 is to
transport specific amino acids through cell membranes to provide nutrients to cells and …