Role of telomere length in human carcinogenesis

A Tsatsakis, T Oikonomopoulou… - International …, 2023 - spandidos-publications.com
Cancer is considered the most important clinical, social and economic issue regarding
cause‑specific disability‑adjusted life years among all human pathologies. Exogenous …

Treatment of central nervous system tumors on combination MR-linear accelerators: review of current practice and future directions

JM Bryant, A Doniparthi, J Weygand, R Cruz-Chamorro… - Cancers, 2023 - mdpi.com
Simple Summary Magnetic resonance imaging (MRI) has several advantages over
computerized tomography (CT) in the treatment planning of central nervous system (CNS) …

Telomeres and aging: on and off the planet!

CE Mason, MA Sierra, HJ Feng, SM Bailey - Biogerontology, 2024 - Springer
Improving human healthspan in our rapidly aging population has never been more
imperative. Telomeres, protective “caps” at the ends of linear chromosomes, are essential for …

Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing

TM Al-Turki, DG Maranon, CB Nelson… - Communications …, 2024 - nature.com
Telomeres are repetitive nucleoprotein complexes at chromosomal termini essential for
maintaining genome stability. Telomeric RNA, or TERRA, is a previously presumed long …

Ad Astra–telomeres in space!

SM Bailey, JJ Luxton, MJ McKenna… - … Journal of Radiation …, 2022 - Taylor & Francis
Purpose My journey to the stars began as I–along with the whole world–stood still and
watched Neil Armstrong take those first small steps on the Moon. Fast forward 50 years and …

The future of biological dosimetry in mass casualty radiation emergency response, personalized radiation risk estimation and space radiation protection

EA Ainsbury, J Moquet, M Sun, S Barnard… - … Journal of Radiation …, 2022 - Taylor & Francis
Purpose The aim of this brief personal, high level review is to consider the state of the art for
biological dosimetry for radiation routine and emergency response, and the potential future …

Telomere dynamics and oxidative stress in Arabidopsis grown in lunar regolith simulant

BB Barcenilla, I Kundel, E Hall, N Hilty… - Frontiers in Plant …, 2024 - frontiersin.org
NASA envisions a future where humans establish a thriving colony on the Moon by 2050.
Plants will be essential for this endeavor, but little is known about their adaptation to …

Normal tissue toxicity prediction: clinical translation on the horizon

SL Kerns, WA Hall, B Marples, CML West - Seminars in Radiation …, 2023 - Elsevier
Improvements in radiotherapy delivery have enabled higher therapeutic doses and
improved efficacy, contributing to the growing number of long-term cancer survivors. These …

A correlation graph attention network for classifying chromosomal instabilities from histopathology whole-slide images

L Liu, Y Wang, J Chang, P Zhang, S Xiong, H Liu - iScience, 2023 - cell.com
The chromosome instability (CIN) is one of the hallmarks of cancer and is closely related to
tumor metastasis. However, the sheer size and resolution of histopathology whole-slide …

Radiation biomarkers: Silver bullet, or wild goose chase?

EA Rutten, C Badie - Journal of Personalized Medicine, 2021 - mdpi.com
Humans have learned to harness the power of radiation for therapeutic ends, with 50% of all
patients diagnosed with cancer undergoing radiotherapy as part of their treatment [1] …