Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central
nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that …

Oxidative stress has been implicated in the etiology and pathobiology of various
neurodegenerative diseases. At baseline, the cells of the nervous system have the capability …

Background Regulating the microglial phenotype is an attractive strategy for treating
diseases of the central nervous system such as depression and anxiety. Gastrodin can …

Oligodendrocytes (ODCs) are myelinating cells of the central nervous system (CNS)
supporting neuronal survival. Oxidants and mitochondrial dysfunction have been suggested …

Astroglia or astrocytes, the most abundant cells in the brain, are interposed between
neuronal synapses and microvasculature in the brain gray matter. They play a pivotal role in …

Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disorder of the central
nervous system (CNS) that remains incurable. Withametelin (WMT), a phytosterol, showed …

Background Chronic cerebral hypoperfusion causes damage to the brain's white matter
underpinning vascular cognitive impairment. Inflammation and oxidative stress have been …

Introduction This paper highlights the relationship of inflammation and oxidative stress as
damage mechanisms of Multiple Sclerosis (MS), considered an inflammatory and …

Multiple sclerosis (MS) encompasses a chronic, irreversible, and predominantly immune-
mediated disease of the central nervous system that leads to axonal degeneration, neuronal …

Ischemic stroke refers to the sudden loss of blood flow in a specific area of the brain. It is the
fifth leading cause of mortality and the leading cause of permanent disability. The …