Latest developments in molecular tracers for fluorescence image-guided cancer surgery

S Hernot, L van Manen, P Debie, JSD Mieog… - The lancet …, 2019 - thelancet.com
Real-time intraoperative guidance is essential during oncological surgery for complete and
safe tumour resection. Fluorescence imaging in the near-infrared spectrum has shown …

Advances in Prostate‐Specific Membrane Antigen (PSMA)‐Targeted Phototheranostics of Prostate Cancer

H Wang, Z He, XA Liu, Y Huang, J Hou… - Small …, 2022 - Wiley Online Library
With the advent of the era of precision medicine, prostate‐specific membrane antigen
(PSMA)‐targeted theranostic strategies have had a profound impact on prostate cancer …

Robot-assisted prostate-specific membrane antigen–radioguided salvage surgery in recurrent prostate cancer using a DROP-IN gamma probe: the first prospective …

HA de Barros, MN van Oosterom, ML Donswijk… - European Urology, 2022 - Elsevier
Background It has been proven that intraoperative prostate-specific membrane antigen
(PSMA)-targeted radioguidance is valuable for the detection of prostate cancer (PCa) …

Emerging fluorescent molecular tracers to guide intra-operative surgical decision-making

P Debie, S Hernot - Frontiers in Pharmacology, 2019 - frontiersin.org
Fluorescence imaging is an emerging technology that can provide real-time information
about the operating field during cancer surgery. Non-specific fluorescent agents, used for …

PET/fluorescence imaging: An overview of the chemical strategies to build dual imaging tools

J Ariztia, K Solmont, NP Moïse, S Specklin… - Bioconjugate …, 2022 - ACS Publications
Molecular imaging is a biomedical research discipline that has quickly emerged to afford the
observation, characterization, monitoring, and quantification of biomarkers and biological …

Cyanine conjugate‐based biomedical imaging probes

Y Li, Y Zhou, X Yue, Z Dai - Advanced Healthcare Materials, 2020 - Wiley Online Library
Cyanine is a class of fluorescent dye with meritorious fluorescence properties and has
motivated numerous researchers to explore its imaging capabilities by miscellaneous …

How molecular imaging will enable robotic precision surgery: the role of artificial intelligence, augmented reality, and navigation

T Wendler, FWB van Leeuwen, N Navab… - European Journal of …, 2021 - Springer
Molecular imaging is one of the pillars of precision surgery. Its applications range from early
diagnostics to therapy planning, execution, and the accurate assessment of outcomes. In …

Radiolabeled PSMA inhibitors

OC Neels, K Kopka, C Liolios, A Afshar-Oromieh - Cancers, 2021 - mdpi.com
Simple Summary Prostate cancer remains one of the leading causes of cancer death in men
worldwide. Despite the recent success in the development and clinical application of …

Recent advances in nuclear and hybrid detection modalities for image-guided surgery

MN Van Oosterom, DDD Rietbergen… - Expert review of …, 2019 - Taylor & Francis
Introduction: Radioguided surgery is an ever-evolving part of nuclear medicine. In fact, this
nuclear medicine sub-discipline actively bridges non-invasive molecular imaging with …

[HTML][HTML] PSMA-targeting agents for radio-and fluorescence-guided prostate cancer surgery

YHW Derks, DWPM Löwik, JPM Sedelaar… - Theranostics, 2019 - ncbi.nlm.nih.gov
Despite recent improvements in imaging and therapy, prostate cancer (PCa) still causes
substantial morbidity and mortality. In surgical treatment, incomplete resection of PCa and …