[HTML][HTML] Metabolic crosstalk in the breast cancer microenvironment
During tumorigenesis, breast tumour cells undergo metabolic reprogramming, which
generally includes enhanced glycolysis, tricarboxylic acid cycle activity, glutaminolysis and …
generally includes enhanced glycolysis, tricarboxylic acid cycle activity, glutaminolysis and …
Lipid droplets in cancer
T Petan - Organelles in Disease, 2020 - Springer
Lipid droplets have a unique structure among organelles consisting of a dense hydrophobic
core of neutral lipids surrounded by a single layer of phospholipids decorated with various …
core of neutral lipids surrounded by a single layer of phospholipids decorated with various …
Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells
AA Al-Khami, L Zheng, L Del Valle, F Hossain… - …, 2017 - Taylor & Francis
Myeloid-derived suppressor cells (MDSC) promote tumor growth by blocking anti-tumor T
cell responses. Recent reports show that MDSC increase fatty acid uptake and fatty acid …
cell responses. Recent reports show that MDSC increase fatty acid uptake and fatty acid …
Identifying off-target effects of etomoxir reveals that carnitine palmitoyltransferase I is essential for cancer cell proliferation independent of β-oxidation
It has been suggested that some cancer cells rely upon fatty acid oxidation (FAO) for energy.
Here we show that when FAO was reduced approximately 90% by pharmacological …
Here we show that when FAO was reduced approximately 90% by pharmacological …
Mammary gland adipocytes in lactation cycle, obesity and breast cancer
The mammary gland (MG) is an exocrine gland present in female mammals responsible for
the production and secretion of milk during the process of lactation. It is mainly composed by …
the production and secretion of milk during the process of lactation. It is mainly composed by …
Cancer-associated adipocytes and breast cancer: intertwining in the tumor microenvironment and challenges for cancer therapy
C Wu, S Dong, R Huang, X Chen - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is the most prevalent cancer in women worldwide, and it
exhibits a growing incidence. An increasing number of studies showed the complex …
exhibits a growing incidence. An increasing number of studies showed the complex …
[HTML][HTML] Sleep duration, sleep quality and the risk of being obese: Evidence from the Australian panel survey
Background Sleep difficulty is an unmet public health concern affecting a vast proportion of
the world's population. Poor sleep duration (short or long sleep length) and quality affect …
the world's population. Poor sleep duration (short or long sleep length) and quality affect …
Breast cancer: mitochondria-centered metabolic alterations in tumor and associated adipose tissue
The close cooperation between breast cancer and cancer-associated adipose tissue (CAAT)
shapes the malignant phenotype, but the role of mitochondrial metabolic reprogramming …
shapes the malignant phenotype, but the role of mitochondrial metabolic reprogramming …
Carnitine palmitoyl transferase 1A is a novel diagnostic and predictive biomarker for breast cancer
Z Tan, Y Zou, M Zhu, Z Luo, T Wu, C Zheng, A Xie… - BMC cancer, 2021 - Springer
Background Carnitine palmitoyl transferase 1A (CPT1A), the key regulator of fatty acid
oxidation, contributes to tumor metastasis and therapeutic resistance. We aimed to identify …
oxidation, contributes to tumor metastasis and therapeutic resistance. We aimed to identify …
Cancer metabolism and intervention therapy
H Zhao, Y Li - Molecular Biomedicine, 2021 - Springer
Metabolic reprogramming with heterogeneity is a hallmark of cancer and is at the basis of
malignant behaviors. It supports the proliferation and metastasis of tumor cells according to …
malignant behaviors. It supports the proliferation and metastasis of tumor cells according to …