Recent trends in protein and peptide-based biomaterials for advanced drug delivery

A Varanko, S Saha, A Chilkoti - Advanced drug delivery reviews, 2020 - Elsevier
Engineering protein and peptide-based materials for drug delivery applications has gained
momentum due to their biochemical and biophysical properties over synthetic materials …

Multicomponent self-assembly as a tool to harness new properties from peptides and proteins in material design

BO Okesola, A Mata - Chemical Society Reviews, 2018 - pubs.rsc.org
Nature is enriched with a wide variety of complex, synergistic, and highly functional protein-
based multicomponent assemblies. As such, nature has served as a source of inspiration for …

Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs

Y Lin, SL Currie, MK Rosen - Journal of Biological Chemistry, 2017 - ASBMB
Liquid–liquid phase separation (LLPS) is thought to contribute to the establishment of many
biomolecular condensates, eukaryotic cell structures that concentrate diverse …

Stimuli-responsive hydrogels for manipulation of cell microenvironment: From chemistry to biofabrication technology

MA Mohamed, A Fallahi, AMA El-Sokkary… - Progress in polymer …, 2019 - Elsevier
Native tissues orchestrate their functions by complex interdependent cascades of
biochemical and biophysical cues that vary spatially and temporally during cellular …

pH-and temperature-sensitive hydrogel nanoparticles with dual photoluminescence for bioprobes

Y Zhao, C Shi, X Yang, B Shen, Y Sun, Y Chen, X Xu… - ACS …, 2016 - ACS Publications
This study demonstrates high contrast and sensitivity by designing a dual-emissive hydrogel
particle system, whose two emissions respond to pH and temperature strongly and …

Injectable tissue integrating networks from recombinant polypeptides with tunable order

S Roberts, TS Harmon, JL Schaal, V Miao, K Li… - Nature materials, 2018 - nature.com
Emergent properties of natural biomaterials result from the collective effects of nanoscale
interactions among ordered and disordered domains. Here, using recombinant sequence …

Biomaterials via peptide assembly: Design, characterization, and application in tissue engineering

VP Gray, CD Amelung, IJ Duti, EG Laudermilch… - Acta biomaterialia, 2022 - Elsevier
A core challenge in biomaterials, with both fundamental significance and technological
relevance, concerns the rational design of bioactive microenvironments. Designed properly …

Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions

LL Li, SL Qiao, WJ Liu, Y Ma, D Wan, J Pan… - Nature …, 2017 - nature.com
Topological structures of bio-architectonics and bio-interfaces play major roles in
maintaining the normal functions of organs, tissues, extracellular matrix, and cells. In-depth …

Thermoresponsive polymer assemblies: from molecular design to theranostics application

SL Qiao, M Mamuti, HW An, H Wang - Progress in Polymer Science, 2022 - Elsevier
Molecule self-assembly is a ubiquitous phenomenon and a key driving force for constructing
nanostructures with diverse morphology and controllable size. Recently, interests in …

Self-assembled peptide nanostructures for functional materials

MS Ekiz, G Cinar, MA Khalily, MO Guler - Nanotechnology, 2016 - iopscience.iop.org
Nature is an important inspirational source for scientists, and presents complex and elegant
examples of adaptive and intelligent systems created by self-assembly. Significant effort has …