A bright future for precision medicine: advances in fluorescent chemical probe design and their clinical application

M Garland, JJ Yim, M Bogyo - Cell chemical biology, 2016 - cell.com
The Precision Medicine Initiative aims to use advances in basic and clinical research to
develop therapeutics that selectively target and kill cancer cells. Under the same doctrine of …

PSMA-targeting imaging and theranostic agents—Current status and future perspective

S Debnath, N Zhou, M McLaughlin, S Rice… - International journal of …, 2022 - mdpi.com
In the past two decades, extensive efforts have been made to develop agents targeting
prostate-specific membrane antigen (PSMA) for prostate cancer imaging and therapy. To …

[HTML][HTML] PSMA ligands for radionuclide imaging and therapy of prostate cancer: clinical status

S Lütje, S Heskamp, AS Cornelissen, TD Poeppel… - Theranostics, 2015 - ncbi.nlm.nih.gov
Prostate cancer (PCa) is the most common malignancy in men worldwide, leading to
substantial morbidity and mortality. At present, imaging of PCa has become increasingly …

Aptamer‐functionalized quantum dots as theranostic nanotools against cancer and bacterial infections: a comprehensive overview of recent trends

F Davodabadi, S Mirinejad… - Biotechnology …, 2023 - Wiley Online Library
Aptamers (Apts) are synthetic nucleic acid ligands that can be engineered to target various
molecules, including amino acids, proteins, and pharmaceuticals. Through a series of …

A perspective on the evolving story of PSMA biology, PSMA-based imaging, and endoradiotherapeutic strategies

DS O'Keefe, DJ Bacich, SS Huang… - Journal of Nuclear …, 2018 - Soc Nuclear Med
In this review, we cover the evolution of knowledge on the biology of prostate-specific
membrane antigen (PSMA) and its translation to therapy. The usual key to discovery is a …

Synthesis and functionalization of hyperbranched polymers for targeted drug delivery

A Kavand, N Anton, T Vandamme, CA Serra… - Journal of Controlled …, 2020 - Elsevier
Hyperbranched polymers (HBPs) have found use in a wide range of applications, such as
optical, electronic and magnetic materials, coatings, additives, supramolecular chemistry …

[HTML][HTML] Prostate-specific membrane antigen as a target for cancer imaging and therapy

AP Kiess, SR Banerjee, RC Mease… - The quarterly journal …, 2015 - ncbi.nlm.nih.gov
The prostate-specific membrane antigen (PSMA) is a molecular target whose use has
resulted in some of the most productive work toward imaging and treating prostate cancer …

The accuracy of 68Ga-PSMA PET/CT in primary lymph node staging in high-risk prostate cancer

C Öbek, T Doğanca, E Demirci, M Ocak… - European journal of …, 2017 - Springer
Purpose To assess the diagnostic accuracy of 68 Ga-PSMA PET in predicting lymph node
(LN) metastases in primary N staging in high-risk and very high-risk nonmetastatic prostate …

The future of PSMA-targeted radionuclide therapy: an overview of recent preclinical research

EAM Ruigrok, WM van Weerden, J Nonnekens… - Pharmaceutics, 2019 - mdpi.com
Prostate specific membrane antigen (PSMA) has become a major focus point in the research
and development of prostate cancer (PCa) imaging and therapeutic strategies using …

Prostate-specific membrane antigen targeted gold nanoparticles for prostate cancer radiotherapy: does size matter for targeted particles?

D Luo, X Wang, S Zeng, G Ramamurthy, C Burda… - Chemical …, 2019 - pubs.rsc.org
Since the introduction of PSA testing, significantly more men have been diagnosed and
treated for prostate cancer. Localized prostate cancer typically is treated with prostatectomy …