Possible mechanisms of lymphopenia in severe tuberculosis
F Li, D Chen, Q Zeng, Y Du - Microorganisms, 2023 - mdpi.com
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (M.
tuberculosis). In lymphopenia, T cells are typically characterized by progressive loss and a …
tuberculosis). In lymphopenia, T cells are typically characterized by progressive loss and a …
Molecular imaging of tuberculosis
IO Lawal, S Abubakar, AO Ankrah… - Seminars in Nuclear …, 2023 - Elsevier
Despite the introduction of many novel diagnostic techniques and newer treatment agents,
tuberculosis (TB) remains a major cause of death from an infectious disease worldwide. With …
tuberculosis (TB) remains a major cause of death from an infectious disease worldwide. With …
Dynamic 18F-Pretomanid PET imaging in animal models of TB meningitis and human studies
Pretomanid is a nitroimidazole antimicrobial active against drug-resistant Mycobacterium
tuberculosis and approved in combination with bedaquiline and linezolid (BPaL) to treat …
tuberculosis and approved in combination with bedaquiline and linezolid (BPaL) to treat …
Angiopep-2 modified exosomes load rifampicin with potential for treating central nervous system tuberculosis
H Li, Y Ding, J Huang, Y Zhao, W Chen… - International Journal …, 2023 - Taylor & Francis
Background Central nervous system tuberculosis (CNS-TB) is the most devastating form of
extrapulmonary tuberculosis. Rifampin (RIF) is a first-line antimicrobial agent with potent …
extrapulmonary tuberculosis. Rifampin (RIF) is a first-line antimicrobial agent with potent …
Dynamic PET reveals compartmentalized brain and lung tissue antibiotic exposures of tuberculosis drugs
Tuberculosis (TB) remains a leading cause of death, but antibiotic treatments for tuberculous
meningitis, the deadliest form of TB, are based on those developed for pulmonary TB and …
meningitis, the deadliest form of TB, are based on those developed for pulmonary TB and …
Trans-nasal brain delivery of anti-TB drugs by methyl-β-cyclodextrin microparticles show efficient mycobacterial clearance from central nervous system
Central nervous system tuberculosis (CNS-TB) is the most severe extra-pulmonary
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
manifestation of tuberculosis (TB), facing significant challenges due to the limited …
Advancing the chemotherapy of tuberculous meningitis: a consensus view
S Wasserman, J Donovan, E Kestelyn… - The Lancet Infectious …, 2025 - thelancet.com
Tuberculous meningitis causes death or disability in approximately 50% of affected
individuals and kills approximately 78 200 adults every year. Antimicrobial treatment is …
individuals and kills approximately 78 200 adults every year. Antimicrobial treatment is …
The development and validation of radiopharmaceuticals targeting bacterial infection
S Alberto, AA Ordonez, C Arjun… - Journal of Nuclear …, 2023 - Soc Nuclear Med
The International Atomic Energy Agency organized a technical meeting at its headquarters
in Vienna, Austria, in 2022 that included 17 experts representing 12 countries, whose …
in Vienna, Austria, in 2022 that included 17 experts representing 12 countries, whose …
The immunogenetics of tuberculosis (TB) susceptibility
Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains the leading cause
of death due to a single bacterial agent, with approximately 10.6 million people developing …
of death due to a single bacterial agent, with approximately 10.6 million people developing …
Linezolid does not improve bactericidal activity of rifampin-containing first-line regimens in animal models of TB meningitis
Tuberculous meningitis (TB meningitis) is the most devastating form of tuberculosis (TB) and
there is a critical need to optimize treatment. Linezolid is approved for multidrug resistant TB …
there is a critical need to optimize treatment. Linezolid is approved for multidrug resistant TB …