Molecular biotechnology has made it possible to explore the potential of plants for different
purposes. The 3'regulatory regions have a great diversity of cis-regulatory elements directly …

Alternative polyadenylation (APA) is how genes choose different sites for 3′ end formation
for mRNAs during transcription. APA often occurs in a tissue‐or developmental stage …

De novo mutations are known to play a prominent role in sporadic disorders with reduced
fitness. We hypothesize that de novo mutations play an important role in severe male …

CSTF2 encodes an RNA-binding protein that is essential for mRNA cleavage and
polyadenylation (C/P). No disease-associated mutations have been described for this gene …

Objectives Melanoma progression involves multiple molecular pathways. In this study, we
explored the effect of immunoglobulin heavy constant gamma 1 (IGHG1) on melanoma …

A vast amount of public RNA-sequencing datasets have been generated and used widely to
study transcriptome mechanisms. These data offer precious opportunity for advancing …

The cleavage stimulation factor subunit complex is involved in the cleavage and
polyadenylation of 3′-end pre-mRNAs that regulate mRNA formation and processing …

X-derived retrogenes contribute to genetic diversity in evolution and are usually specifically
expressed in testis and perform important functions during spermatogenesis. Ubl4b is an …

During embryonic development, a number of genetic cues act to generate neuronal
diversity. While intrinsic transcriptional cascades are well-known to control neuronal sub …

Male infertility is multifactorial and presents with heterogeneous phenotypic features.
Genetic factors are responsible for up to 15% of the male infertility cases. Loss of the Cstf2t …