The neuronal circuits of the basolateral amygdala (BLA) are crucial for acquisition, consolidation, retrieval, and extinction of associative emotional memories. Synaptic plasticity …
XD Yu, Y Zhu, QX Sun, F Deng, J Wan, D Zheng… - Nature …, 2022 - nature.com
Anxiety-like behaviors in mice include social avoidance and avoidance of bright spaces. Whether these features are distinctly regulated is unclear. We demonstrate that in mice …
The empathic ability to vicariously experience the other's fearful situation, a process called observational fear (OF), is critical to survive in nature and function in society. OF can be …
Memories about sensory experiences are tightly linked to the context in which they were formed. Memory contextualization is fundamental for the selection of appropriate behavioral …
AJ McDonald, DD Mott - Journal of neuroscience research, 2017 - Wiley Online Library
The amygdalar nuclear complex and hippocampal/parahippocampal region are key components of the limbic system that play a critical role in emotional learning and memory …
Emotions are temporally dynamic, but the persistence of emotions outside of their appropriate temporal context is detrimental to health and well-being. Yet, precisely how …
J Zheng, RF Stevenson, BA Mander, L Mnatsakanyan… - Neuron, 2019 - cell.com
How do we remember emotional events? While emotion often leads to vivid recollection, the precision of emotional memories can be degraded, especially when discriminating among …
Despite a wealth of clinical and preclinical data implicating the serotonin (5-HT) system in fear-related affective disorders, a precise definition of this neuromodulator's role in fear …
Learned fear and safety are associated with distinct oscillatory states in the basolateral amygdala (BLA) and medial prefrontal cortex (mPFC). To determine if and how these …