Development and clinical translation of tubular constructs for tracheal tissue engineering: a review

L Soriano, T Khalid, D Whelan… - European …, 2021 - Eur Respiratory Soc
Effective restoration of extensive tracheal damage arising from cancer, stenosis, infection or
congenital abnormalities remains an unmet clinical need in respiratory medicine. The …

Three-dimensional models of the lung: past, present and future: a mini review

C Sen, D Freund, BN Gomperts - Biochemical Society …, 2022 - portlandpress.com
Respiratory diseases are a major reason for death in both men and women worldwide. The
development of therapies for these diseases has been slow and the lack of relevant human …

Experimental tracheal replacement using 3-dimensional bioprinted artificial trachea with autologous epithelial cells and chondrocytes

JH Park, JK Yoon, JB Lee, YM Shin, KW Lee, SW Bae… - Scientific reports, 2019 - nature.com
Various treatment methods for tracheal defects have been attempted, such as artificial
implants, allografts, autogenous grafts, and tissue engineering; however, no perfect method …

[HTML][HTML] Mechanics of pulmonary airways: linking structure to function through constitutive modeling, biochemistry, and histology

M Eskandari, TM Nordgren, GD O'Connell - Acta biomaterialia, 2019 - Elsevier
Breathing involves fluid-solid interactions in the lung; however, the lack of experimental data
inhibits combining the mechanics of air flow to airway deformation, challenging the …

Effects of tissue degradation by collagenase and elastase on the biaxial mechanics of porcine airways

CA Mariano, S Sattari, GO Ramirez, M Eskandari - Respiratory Research, 2023 - Springer
Background Common respiratory illnesses, such as emphysema and chronic obstructive
pulmonary disease, are characterized by connective tissue damage and remodeling. Two …

Mechanical properties and in vitro evaluation of thermoplastic polyurethane and polylactic acid blend for fabrication of 3D filaments for tracheal tissue engineering

A Abdul Samat, ZA Abdul Hamid, M Jaafar, BH Yahaya - Polymers, 2021 - mdpi.com
Surgical reconstruction of extensive tracheal lesions is challenging. It requires a
mechanically stable, biocompatible, and nontoxic material that gradually degrades. One of …

Psidium guajava L. phenolic compound-reinforced lamellar scaffold for tracheal tissue engineering

VA Amaral, JF de Souza, TFR Alves… - Drug Delivery and …, 2024 - Springer
The aim of this work was to develop a dense lamellar scaffold, as a biomimetic material with
potential applications in the regeneration of tracheal tissue after surgical tumor resection …

Anesthesia for resection and reconstruction of the trachea and carina

AM Smeltz, M Bhatia, H Arora, J Long… - Journal of Cardiothoracic …, 2020 - Elsevier
Airway surgery poses a host of unique challenges to both the surgical and anesthesiology
teams. Accordingly, there are a variety of surgical, anesthetic, and airway management …

Bioengineering and clinical translation of human lung and its components

ID Derman, YP Singh, S Saini, M Nagamine… - Advanced …, 2023 - Wiley Online Library
Clinical lung transplantation has rapidly established itself as the gold standard of treatment
for end‐stage lung diseases in a restricted group of patients since the first successful lung …

Fabrication and characterization of customized tubular scaffolds for tracheal tissue engineering by using solvent based 3D printing on predefined template

R Kandi, PM Pandey, M Majood… - Rapid Prototyping …, 2021 - emerald.com
Purpose This paper aims to discuss the successful fabrication of customized tubular
scaffolds for tracheal tissue engineering with a novel route using solvent-based extrusion 3D …