Lysozymes in the animal kingdom
L Callewaert, CW Michiels - Journal of biosciences, 2010 - Springer
Abstract Lysozymes (EC 3.2. 1.17) are hydrolytic enzymes, characterized by their ability to
cleave the β-(1, 4)-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine …
cleave the β-(1, 4)-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine …
Evolution of host innate defence: insights from Caenorhabditis elegans and primitive invertebrates
The genetically tractable model organism Caenorhabditis elegans was first used to model
bacterial virulence in vivo a decade ago. Since then, great strides have been made in …
bacterial virulence in vivo a decade ago. Since then, great strides have been made in …
Insights into the red algae and eukaryotic evolution from the genome of Porphyra umbilicalis (Bangiophyceae, Rhodophyta)
Porphyra umbilicalis (laver) belongs to an ancient group of red algae (Bangiophyceae), is
harvested for human food, and thrives in the harsh conditions of the upper intertidal zone …
harvested for human food, and thrives in the harsh conditions of the upper intertidal zone …
Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genes
O Visvikis, N Ihuegbu, SA Labed, LG Luhachack… - Immunity, 2014 - cell.com
Animal host defense against infection requires the expression of defense genes at the right
place and the right time. Understanding such tight control of host defense requires the …
place and the right time. Understanding such tight control of host defense requires the …
[HTML][HTML] Inactivation of conserved C. elegans genes engages pathogen-and xenobiotic-associated defenses
The nematode C. elegans is attracted to nutritious bacteria and is repelled by pathogens
and toxins. Here we show that RNAi and toxin-mediated disruption of core cellular activities …
and toxins. Here we show that RNAi and toxin-mediated disruption of core cellular activities …
p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans
The PMK-1 p38 mitogen-activated protein kinase pathway and the DAF-2–DAF-16 insulin
signaling pathway control Caenorhabditis elegans intestinal innate immunity. pmk-1 loss-of …
signaling pathway control Caenorhabditis elegans intestinal innate immunity. pmk-1 loss-of …
Distinct Pathogenesis and Host Responses during Infection of C. elegans by P. aeruginosa and S. aureus
JE Irazoqui, ER Troemel, RL Feinbaum… - PLoS …, 2010 - journals.plos.org
The genetically tractable model host Caenorhabditis elegans provides a valuable tool to
dissect host-microbe interactions in vivo. Pseudomonas aeruginosa and Staphylococcus …
dissect host-microbe interactions in vivo. Pseudomonas aeruginosa and Staphylococcus …
Myeloid C-type lectins in innate immunity
C-type lectins expressed on myeloid cells comprise a family of proteins that share a common
structural motif, and some act as receptors in pathogen recognition. But just as the presence …
structural motif, and some act as receptors in pathogen recognition. But just as the presence …
Insights from the worm: the C. elegans model for innate immunity
MA Ermolaeva, B Schumacher - Seminars in immunology, 2014 - Elsevier
The nematode worm Caenorhabditis elegans comprises an ancestral immune system. C.
elegans recognizes and responds to viral, bacterial, and fungal infections. Components of …
elegans recognizes and responds to viral, bacterial, and fungal infections. Components of …
Distinct innate immune responses to infection and wounding in the C. elegans epidermis
N Pujol, S Cypowyj, K Ziegler, A Millet, A Astrain… - Current Biology, 2008 - cell.com
Background In many animals, the epidermis is in permanent contact with the environment
and represents a first line of defense against pathogens and injury. Infection of the …
and represents a first line of defense against pathogens and injury. Infection of the …