Biomechanics and biophysics of cancer cells

S Suresh - Acta biomaterialia, 2007 - Elsevier
The past decade has seen substantial growth in research into how changes in the
biomechanical and biophysical properties of cells and subcellular structures influence, and …

Shape and biomechanical characteristics of human red blood cells in health and disease

M Diez-Silva, M Dao, J Han, CT Lim, S Suresh - MRS bulletin, 2010 - cambridge.org
The biconcave shape and corresponding deformability of the human red blood cell (RBC) is
an essential feature of its biological function. This feature of RBCs can be critically affected …

Cell mechanics: principles, practices, and prospects

E Moeendarbary, AR Harris - Wiley Interdisciplinary Reviews …, 2014 - Wiley Online Library
Cells generate and sustain mechanical forces within their environment as part of their
normal physiology. They are active materials that can detect mechanical stimulation by the …

Cerebral Plasmodium falciparum malaria: The role of PfEMP1 in its pathogenesis and immunity, and PfEMP1‐based vaccines to prevent it

AR Jensen, Y Adams, L Hviid - Immunological reviews, 2020 - Wiley Online Library
Malaria, a mosquito‐borne infectious disease caused by parasites of the genus Plasmodium
continues to be a major health problem worldwide. The unicellular Plasmodium‐parasites …

Oxidative stress in malaria

S Percário, DR Moreira, BAQ Gomes… - International journal of …, 2012 - mdpi.com
Malaria is a significant public health problem in more than 100 countries and causes an
estimated 200 million new infections every year. Despite the significant effort to eradicate …

Mechanics of the human red blood cell deformed by optical tweezers

M Dao, CT Lim, S Suresh - Journal of the Mechanics and Physics of Solids, 2003 - Elsevier
The mechanical deformation characteristics of living cells are known to influence strongly
their chemical and biological functions and the onset, progression and consequences of a …

Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria

S Suresh, J Spatz, JP Mills, A Micoulet, M Dao, CT Lim… - Acta biomaterialia, 2005 - Elsevier
We investigate connections between single-cell mechanical properties and subcellular
structural reorganization from biochemical factors in the context of two distinctly different …

Mechanical models for living cells—a review

CT Lim, EH Zhou, ST Quek - Journal of biomechanics, 2006 - Elsevier
As physical entities, living cells possess structural and physical properties that enable them
to withstand the physiological environment as well as mechanical stimuli occurring within …

Refractive index maps and membrane dynamics of human red blood cells parasitized by Plasmodium falciparum

YK Park, M Diez-Silva, G Popescu… - Proceedings of the …, 2008 - National Acad Sciences
Parasitization by malaria-inducing Plasmodium falciparum leads to structural, biochemical,
and mechanical modifications to the host red blood cells (RBCs). To study these …

A newly discovered protein export machine in malaria parasites

TF de Koning-Ward, PR Gilson, JA Boddey, M Rug… - Nature, 2009 - nature.com
Several hundred malaria parasite proteins are exported beyond an encasing vacuole and
into the cytosol of the host erythrocyte, a process that is central to the virulence and viability …