Phloretin: a comprehensive review of its potential against diabetes and associated complications
Objectives Phloretin is ubiquitous in apples (Malus domestica) and other fruits and has
potential antidiabetic properties. Considering the preclinical potential of phloretin, its …
potential antidiabetic properties. Considering the preclinical potential of phloretin, its …
High-mobility group box 1 and its related receptors: potential therapeutic targets for contrast-induced acute kidney injury
C Mo, Q Huang, L Li, Y Long, Y Shi, Z Lu, N Wu… - … Urology and Nephrology, 2024 - Springer
Percutaneous coronary intervention (PCI) is a crucial diagnostic and therapeutic approach
for coronary heart disease. Contrast agents' exposure during PCI is associated with a risk of …
for coronary heart disease. Contrast agents' exposure during PCI is associated with a risk of …
Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: a potential therapeutic approach targeting TLR4-induced inflammation
Abstract Aim Targeting Toll-like receptor 4 (TLR4) and Angiotensin II type 1 receptor (AT1R)
could provide renoprotection during acute kidney injury (AKI) mainly by regulating …
could provide renoprotection during acute kidney injury (AKI) mainly by regulating …
Renoprotective effect of esculetin against ischemic acute kidney injury-diabetic comorbidity
Mitophagy maintains cellular homeostasis by eliminating damaged mitochondria.
Accumulated damaged mitochondria can lead to oxidative stress and cell death. Induction of …
Accumulated damaged mitochondria can lead to oxidative stress and cell death. Induction of …
[HTML][HTML] Empagliflozin mitigates ponatinib-induced cardiotoxicity by restoring the connexin 43-autophagy pathway
L Mattii, S Moscato, C Ippolito, E Polizzi, G Novo… - Biomedicine & …, 2024 - Elsevier
Background Empagliflozin (EMPA), a selective sodium-glucose cotransporter type 2
(SGLT2) inhibitor, has been shown to reduce major adverse cardiovascular events in …
(SGLT2) inhibitor, has been shown to reduce major adverse cardiovascular events in …
Management of inflammaging in kidney diseases: focusing on the current investigational drugs
Introduction To improve kidney disease treatments, it is crucial to understand how
inflammaging affects patients´ longevity. We could potentially slow down kidney disease …
inflammaging affects patients´ longevity. We could potentially slow down kidney disease …
Phloretamide Protects against Diabetic Kidney Damage and Dysfunction in Diabetic Rats by Attenuating Hyperglycemia and Hyperlipidemia, Suppressing NF-κβ, and …
R Al-Hussan, NA Albadr, GM Alshammari, SA Almasri… - Pharmaceutics, 2024 - mdpi.com
Potent hypoglycemic and antioxidant effects were recently reported for the apple-derived
phenolic compound phloretamide (PLTM). The renoprotective effects of this compound are …
phenolic compound phloretamide (PLTM). The renoprotective effects of this compound are …
Network pharmacology combined with molecular docking and dynamics to assess the synergism of esculetin and phloretin against acute kidney injury-diabetes …
Acute kidney injury (AKI) is a global health concern with high incidence and mortality, where
diabetes further worsens the condition. The available treatment options are not uniformly …
diabetes further worsens the condition. The available treatment options are not uniformly …
The Effect of Sodium??? Glucose Co-Transporter-2 Inhibitors in Contrast-Induced Acute Kidney Injury: A Systematic Review and Meta-Analysis
MRH Rafsanjani, K Rezvanfar, D Saghafi… - The International …, 2024 - tinnitusjournal.com
Background and Aims: Contrast-Induced Acute Kidney Injury (CI-AKI) is the third leading
cause of hospital-acquired renal damage, associated with increased mortality and morbidity …
cause of hospital-acquired renal damage, associated with increased mortality and morbidity …