Connecting the immune system, systemic chronic inflammation and the gut microbiome: the role of sex

L Rizzetto, F Fava, KM Tuohy, C Selmi - Journal of autoimmunity, 2018 - Elsevier
Unresolved low grade systemic inflammation represents the underlying pathological
mechanism driving immune and metabolic pathways involved in autoimmune diseases …

Fructose and NAFLD: the multifaceted aspects of fructose metabolism

P Jegatheesan, JP De Bandt - Nutrients, 2017 - mdpi.com
Among various factors, such as an unhealthy diet or a sedentarity lifestyle, excessive
fructose consumption is known to favor nonalcoholic fatty liver disease (NAFLD), as fructose …

Gut microbial profile is altered in primary biliary cholangitis and partially restored after UDCA therapy

R Tang, Y Wei, Y Li, W Chen, H Chen, Q Wang, F Yang… - Gut, 2018 - gut.bmj.com
Objective A close relationship between gut microbiota and some chronic liver disorders has
recently been described. Herein, we systematically performed a comparative analysis of the …

The dormant blood microbiome in chronic, inflammatory diseases

M Potgieter, J Bester, DB Kell… - FEMS microbiology …, 2015 - academic.oup.com
Blood in healthy organisms is seen as a 'sterile'environment: it lacks proliferating microbes.
Dormant or not-immediately-culturable forms are not absent, however, as intracellular …

Bile acids and intestinal microbiota in autoimmune cholestatic liver diseases

Y Li, R Tang, PSC Leung, ME Gershwin, X Ma - Autoimmunity reviews, 2017 - Elsevier
Autoimmune cholestatic liver diseases, including primary biliary cholangitis (PBC) and
primary sclerosing cholangitis (PSC), are manifested as an impairment of normal bile flow …

[HTML][HTML] Behçet's syndrome patients exhibit specific microbiome signature

C Consolandi, S Turroni, G Emmi, M Severgnini… - Autoimmunity …, 2015 - Elsevier
Background and aims Behçet syndrome is a systemic inflammatory condition characterized
by muco-cutaneous and ocular manifestations, with central nervous system, vascular and/or …

Psychological stress, intestinal barrier dysfunctions, and autoimmune disorders: an overview

H Ilchmann-Diounou, S Menard - Frontiers in immunology, 2020 - frontiersin.org
Autoimmune disorders (ADs) are multifactorial diseases involving, genetic, epigenetic, and
environmental factors characterized by an inappropriate immune response toward self …

[HTML][HTML] Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1

HC Jeffery, B Van Wilgenburg, A Kurioka, K Parekh… - Journal of …, 2016 - Elsevier
Background & Aims Mucosal-Associated Invariant T (MAIT) cells are innate-like T cells
characterised by the invariant TCR-chain, Vα7. 2-Jα33, and are restricted by MR1, which …

[HTML][HTML] Polyphenols synergistic drugs to ameliorate non-alcoholic fatty liver disease via signal pathway and gut microbiota: A review

H Li, J Liang, M Han, Z Gao - Journal of Advanced Research, 2024 - Elsevier
Background Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease
with an increasing incidence worldwide. Single drug therapy may have toxic side effects and …

[HTML][HTML] The gut-liver axis in immune remodeling: new insight into liver diseases

X Yang, D Lu, J Zhuo, Z Lin, M Yang… - International journal of …, 2020 - ncbi.nlm.nih.gov
The gut microbiota consists of a dynamic multispecies community of bacteria, fungi, archaea,
and protozoans, playing a fundamental role in the induction, training, and function of the …