Mitochondria-targeted triphenylphosphonium-based compounds: syntheses, mechanisms of action, and therapeutic and diagnostic applications
Mitochondria are recognized as one of the most important targets for new drug design in
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
cancer, cardiovascular, and neurological diseases. Currently, the most effective way to …
Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes
Chronic manganese (Mn) exposure induces neurotoxicity, which is characterized by
Parkinsonian symptoms resulting from impairment in the extrapyramidal motor system of the …
Parkinsonian symptoms resulting from impairment in the extrapyramidal motor system of the …
[HTML][HTML] Mitochondrial homeostasis regulation: A promising therapeutic target for Parkinson's disease
MF Yao, T Dang, HJ Wang, XZ Zhu, C Qiao - Behavioural Brain Research, 2024 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disease characterized by progressive loss
of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) and the …
of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) and the …
NADPH Oxidase Mediates Membrane Androgen Receptor–Induced Neurodegeneration
MAA Tenkorang, P Duong, RL Cunningham - Endocrinology, 2019 - academic.oup.com
Oxidative stress (OS) is a common characteristic of several neurodegenerative disorders,
including Parkinson disease (PD). PD is more prevalent in men than in women, indicating …
including Parkinson disease (PD). PD is more prevalent in men than in women, indicating …
Increased formation of reactive oxygen species during tumor growth: Ex vivo low-temperature EPR and in vivo bioluminescence analyses
Previous studies have shown that reactive oxygen species (ROS) such as superoxide or
hydrogen peroxide generated at low levels can exert a tumor-promoting role via a redox …
hydrogen peroxide generated at low levels can exert a tumor-promoting role via a redox …
[PDF][PDF] Apocynin as an antidepressant agent: in vivo behavior and oxidative parameters modulation
DP Dalenogare, NS Schiefelbein, MFP Fialho… - academia.edu
Depression is one of the most common mood disorders, which affects one in six people at
some point in life. However, the treatment of this disease is still a challenge. Chronic …
some point in life. However, the treatment of this disease is still a challenge. Chronic …
[引用][C] Manuscript in progress; to be submitted to Acta Biomaterialia in 2017
B Schlichtmann, S Ghaisas, R Nelson, M Panthani… - Targeted nano-carriers to …, 2017