Targeted anticancer drugs block cancer cell growth by interfering with specific signaling
pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing …

Simple Summary Nowadays patients affected by locally advanced breast cancer and
particular subtypes of early breast cancer may benefit from neoadjuvant chemotherapy …

Digital twins employ mathematical and computational models to virtually represent a
physical object (eg, planes and human organs), predict the behavior of the object, and …

This protocol describes a complete data acquisition, analysis and computational forecasting
pipeline for employing quantitative MRI data to predict the response of locally advanced …

Simple Summary The recruitment of new vasculature via angiogenesis is a critical
component of tumor development, which fundamentally influences tumor growth and …

Interstitial brachytherapy (BT) is generally used for the treatment of well-confined solid
tumors. One example of this is in the treatment of prostate tumors by permanent placement …

Simple Summary Tumor heterogeneity influences tumor progression and response to
therapy, introducing a significant challenge in the treatment of breast cancer. We employed …

Medical digital twins are computational models of human biology relevant to a given medical
condition, which are tailored to an individual patient, thereby predicting the course of …

Copper, a vital trace element, orchestrates diverse cellular processes ranging from energy
production to antioxidant defense and angiogenesis. Copper metabolism and cuproptosis …

Objective: This study establishes a fluid dynamics model personalized with patient-specific
imaging data to optimize neoadjuvant therapy (ie, doxorubicin) protocols for breast cancers …