The physiology of inflammatory response is modified by the aging process and is
substantially affected by multimorbidity and disability. Infection is the most frequent cause of …

Importance The optimal duration of antibiotic treatment for community-acquired pneumonia
(CAP) has not been well established. Objective To validate Infectious Diseases Society of …

Beta-lactam antibiotics form the backbone of treatment for Gram-negative pneumonia in
mechanically ventilated patients in the intensive care unit. However, this beta-lactam …

High-dose chemotherapy has long been advocated as a means of controlling drug
resistance in infectious diseases but recent empirical studies have begun to challenge this …

Objective Streptococcus pneumoniae is the most frequent bacterial pathogen isolated in
subjects with Community-acquired pneumonia (CAP) worldwide. Limited data are available …

Background In community-acquired pneumonia (CAP), the role of biomarkers to shorten
duration of antibiotic treatment has not been firmly established. We assessed the …

Rationale: Assessment of the inflammatory response can help the decision-making process
when diagnosing community-acquired pneumonia (CAP), but there is a lack of information …

Hospital-acquired pneumonia (HAP) is a frequent cause of nosocomial infections,
responsible for great morbidity and mortality worldwide. The majority of studies on HAP have …

Historically, durations of antimicrobial therapy for common infections have been largely
driven by habits or cultural norms rather than robust scientific data (1, 2). In general …

Skin and soft tissue infections (SSTIs) are a common cause of hospital admission among
elderly patients, and traditionally have been divided into complicated and uncomplicated …