Targeted Drug Delivery: From Chemistry to Robotics at Small Scales

M Kim, JD Nicholas, J Puigmartí-Luis… - Annual Review of …, 2024 - annualreviews.org
The limited bioavailability, susceptibility to degradation, and adverse side effects of novel
drugs often hinder their effective administration. Nanoparticles, with customizable properties …

Analysis of magnetic interaction in remotely controlled magnetic devices and its application to a capsule robot for drug delivery

F Munoz, G Alici, H Zhou, W Li… - IEEE/ASME Transactions …, 2017 - ieeexplore.ieee.org
In this paper, we present the 3-D analysis of the torque transmitted to a small permanent
magnet that is embedded in a capsule robot to achieve targeted drug delivery. This analysis …

Selective motion control of a novel magnetic-driven minirobot with targeted drug sustained-release function

Z Wang, S Guo, J Guo, Q Fu, L Zheng… - … ASME Transactions on …, 2021 - ieeexplore.ieee.org
In this article, we propose a novel magnetic-actuated multimodule drug sustained-release
minirobot (DSM) manipulated by an external rotating electromagnetic field. The structure of …

Effective locomotion and precise unclogging motion of an untethered flexible-legged magnetic robot for vascular diseases

W Lee, J Nam, J Kim, E Jung… - IEEE Transactions on …, 2017 - ieeexplore.ieee.org
We propose an untethered flexible-legged magnetic robot (FLMR) manipulated by an
external rotating magnetic field (ERMF) to generate effective locomotion and precise …

Magnetic helical robot for targeted drug-delivery in tubular environments

J Nam, W Lee, J Kim, G Jang - IEEE/ASME Transactions on …, 2017 - ieeexplore.ieee.org
We propose a novel magnetic helical robot (HR) that can helically navigate, release a drug
to a target area, and generate a mechanical drilling motion to unclog tubular structures of the …

Rapid manufacturing of micro-drilling devices using FFF-type 3D printing technology

S Park, B Ko, H Lee, H So - Scientific Reports, 2021 - nature.com
Micro-drilling devices with different blade shapes were fabricated with a rapid and facile
manufacturing process using three-dimensional (3D) printing technology. The 3D-printed …

Magnetic navigation system utilizing resonant effect to enhance magnetic field applied to magnetic robots

J Nam, W Lee, B Jang, G Jang - IEEE Transactions on Industrial …, 2017 - ieeexplore.ieee.org
We propose a novel magnetic navigation system (MNS) with the resonant effect of an RLC
circuit to generate large magnetic field in high frequency. The variable capacitors of the …

Selective motion control of a crawling magnetic robot system for wireless self-expandable stent delivery in narrowed tubular environments

W Lee, J Nam, B Jang, G Jang - IEEE Transactions on Industrial …, 2016 - ieeexplore.ieee.org
A novel crawling magnetic robot system manipulated by a magnetic navigation system is
proposed for wireless self-expandable stent delivery in narrowed tubular environments. The …

Insertion, Retrieval and Performance Study of Miniature Magnetic Rotating Swimmers for the Treatment of Thrombi

Y Lu, J Ramos, MG Ghosn, DJ Shah… - 2023 IEEE/RSJ …, 2023 - ieeexplore.ieee.org
Miniature Magnetic Rotating Swimmers (MMRSs) are untethered machines containing
magnetic materials. An external rotating magnetic field produces a torque on the swimmers …

Selective navigating and unclogging motions of an intravascular helical magnetic millirobot actuated by external biaxial rotating magnetic fields

S Jeon, J Nam, W Lee, G Jang - IEEE/ASME Transactions on …, 2017 - ieeexplore.ieee.org
Intravascular helical magnetic millirobots (IHMMs) capable of navigating in and unclogging
human blood vessels have been widely investigated as a possible means for the treatment …