[HTML][HTML] Neural signal propagation atlas of Caenorhabditis elegans

F Randi, AK Sharma, S Dvali, AM Leifer - Nature, 2023 - nature.com
Establishing how neural function emerges from network properties is a fundamental problem
in neuroscience. Here, to better understand the relationship between the structure and the …

Biosensors for odor detection: A review

H Deng, T Nakamoto - Biosensors, 2023 - mdpi.com
Animals can easily detect hundreds of thousands of odors in the environment with high
sensitivity and selectivity. With the progress of biological olfactory research, scientists have …

Dissecting the genetic landscape of GPCR signaling through phenotypic profiling in C. elegans

L Pu, J Wang, Q Lu, L Nilsson, A Philbrook… - Nature …, 2023 - nature.com
G protein-coupled receptors (GPCRs) mediate responses to various extracellular and
intracellular cues. However, the large number of GPCR genes and their substantial …

Chemosensory detection of polyamine metabolites guides C. elegans to nutritive microbes

B Brissette, L Ficaro, C Li, DR Jones… - Science …, 2024 - science.org
Much is known about molecular mechanisms by which animals detect pathogenic microbes,
but how animals sense beneficial microbes remains poorly understood. The roundworm …

Intricate response dynamics enhances stimulus discrimination in the resource-limited C. elegans chemosensory system

E Bokman, CO Pritz, R Ruach, E Itskovits, H Sharvit… - BMC biology, 2024 - Springer
Background Sensory systems evolved intricate designs to accurately encode perplexing
environments. However, this encoding task may become particularly challenging for animals …

[HTML][HTML] Advanced Neural Functional Imaging in C. elegans Using Lab-on-a-Chip Technology

Y Kwon, J Kim, YB Son, SA Lee, SS Choi, Y Cho - Micromachines, 2024 - mdpi.com
The ability to perceive and adapt to environmental changes is crucial for the survival of all
organisms. Neural functional imaging, particularly in model organisms, such as …

TWISP: a transgenic worm for interrogating signal propagation in Caenorhabditis elegans

AK Sharma, F Randi, S Kumar, S Dvali, AM Leifer - Genetics, 2024 - academic.oup.com
Genetically encoded optical indicators and actuators of neural activity allow for all-optical
investigations of signaling in the nervous system. But commonly used indicators, actuators …

A high-throughput behavioral screening platform for measuring chemotaxis by C. elegans

E Fryer, S Guha, LE Rogel-Hernandez… - Plos …, 2024 - journals.plos.org
Throughout history, humans have relied on plants as a source of medication, flavoring, and
food. Plants synthesize large chemical libraries and release many of these compounds into …

The nematode worm C. elegans chooses between bacterial foods as if maximizing economic utility

A Katzen, HK Chung, WT Harbaugh, C Della Iacono… - Elife, 2023 - elifesciences.org
In value-based decision making, options are selected according to subjective values
assigned by the individual to available goods and actions. Despite the importance of this …

Olfactory combinatorial coding supports risk-reward decision making in C. elegans

MZH Saad, WG Ryan, CA Edwards, BN Szymanski… - bioRxiv, 2024 - biorxiv.org
Vertebrate and insect olfactory systems generate diversity in odor perception using
combinatorial coding, where individual odorant molecules activate unique but overlapping …