Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Calpain as a therapeutic target in traumatic brain injury

KE Saatman, J Creed, R Raghupathi - Neurotherapeutics, 2010 - Springer
The family of calcium-activated neutral proteases, calpains, appears to play a key role in
neuropathologic events following traumatic brain injury (TBI). Neuronal calpain activation …

Calpain in the CNS: from synaptic function to neurotoxicity

J Liu, MC Liu, KKW Wang - Science Signaling, 2008 - science.org
The calpains are a class of cellular cysteine proteases that require calcium and are
functionally active at neutral pH. Calpain activation can take place in two modes: controlled …

Slip chip device and methods

RF Ismagilov, W Du, L Li, F Shen, KPF Nichols… - US Patent …, 2016 - Google Patents
A device is described having a first surface having a plurality of first areas and a second
surface having a plurality of second areas. The first surface and the second surface are …

Mechanistic role of calpains in postischemic neurodegeneration

MB Bevers, RW Neumar - Journal of Cerebral Blood Flow & …, 2008 - journals.sagepub.com
The calpain family of proteases is causally linked to postischemic neurodegeneration.
However, the precise mechanisms by which calpains contribute to postischemic neuronal …

Opening Pandora's Jar: A Primer on the Putative Roles of Crmp2 In A Panoply of Neurodegenerative, Sensory and Motor Neuron, and Central Disorders

R Khanna, SM Wilson, JM Brittain, J Weimer… - Future …, 2012 - Taylor & Francis
CRMP2, also known as DPYSL2/DRP2, Unc-33, Ulip or TUC2, is a cytosolic phosphoprotein
that mediates axon/dendrite specification and axonal growth. Mapping the CRMP2 …

CRMP2 protein SUMOylation modulates NaV1. 7 channel trafficking

ET Dustrude, SM Wilson, W Ju, Y Xiao… - Journal of Biological …, 2013 - ASBMB
Voltage-gated sodium channel (NaV) trafficking is incompletely understood. Post-
translational modifications of NaVs and/or auxiliary subunits and protein-protein interactions …

Neuroprotective peptides fused to arginine-rich cell penetrating peptides: Neuroprotective mechanism likely mediated by peptide endocytic properties

BP Meloni, D Milani, AB Edwards, RS Anderton… - Pharmacology & …, 2015 - Elsevier
Several recent studies have demonstrated that TAT and other arginine-rich cell penetrating
peptides (CPPs) have intrinsic neuroprotective properties in their own right. Examples, we …

Identification of Proteins Differentially Expressed in the Striatum by Melatonin in a Middle Cerebral Artery Occlusion Rat Model—a Proteomic and in silico Approach

FA Shah, A Zeb, T Ali, T Muhammad… - Frontiers in …, 2018 - frontiersin.org
Ischemic stroke is characterized by permanent or transient obstruction of blood flow, which
initiates a cascading pathological process, starting from acute ATP loss to subsequent …

Permissive and repulsive cues and signalling pathways of axonal outgrowth and regeneration

ST Hou, SX Jiang, RA Smith - International review of cell and molecular …, 2008 - Elsevier
Successful axonal outgrowth in the adult central nervous system (CNS) is central to the
process of nerve regeneration and brain repair. To date, much of the knowledge on axonal …