Peptoids (N-substituted polyglycines and extended peptoids with variant backbone amino-
acid monomer units) are oligomeric synthetic polymers that are becoming a valuable …

Macrocyclic constraints are often employed to rigidify the conformation of flexible oligomeric
systems. This approach has recently been used to organize the structure of peptoid …

Bioinspired polymeric materials are attracting increasing attention due to significant
advantages over their natural counterparts: the ability to precisely tune their structures over a …

Peptoids, or oligomers of N-substituted glycines, are a class of foldamers that have shown
extraordinary functional potential since their inception nearly two decades ago. However …

Non-natural peptide analogs have significant potential for the development of new materials
and pharmacologically active ligands. One such architecture, the β-peptoids (N-alkyl-β …

Delineating the relationships between sequence, structure, and function in biopolymers is
critical to our understanding of fundamental biochemical interactions. These relationships …

Access to homogeneous and discrete folded peptoid structures primarily depends on control
of the cis/trans isomerism of backbone tertiary amides. This can be achieved by designing …

Conformationally ordered synthetic oligomers, also called “foldamers”, have attracted
considerable attention in recent years owing to their ability to mimic the structural …

The development of a continuous flow multistep strategy for the synthesis of linear peptoids
and their subsequent macrocyclization via Click chemistry is described. The central …

Abstract β-Peptoids are peptidomimetics based on N-alkylated β-aminopropionic acid
residues (or N-alkyl-β-alanines). This type of peptide mimic has previously been …