In vertebrates, multiciliated cells (MCCs) are terminally differentiated cells that line the
airway tracts, brain ventricles, and reproductive ducts. Each MCC contains dozens to …

The analysis of the single-cell transcriptome has emerged as a powerful tool to gain insights
of the basic mechanisms of health and disease. It is widely used to reveal the cellular …

Neural crest cells exemplify cellular diversification from a multipotent progenitor population.
However, the full sequence of early molecular choices orchestrating the emergence of …

Multiciliated cells (MCCs) are epithelial cells that control body fluid flow and contribute to the
clearance of pathogenic microbes and other particles from the airways, egg transport in …

The TMEM16A chloride channel is proposed as a therapeutic target in cystic fibrosis, where
activation of this ion channel might restore airway surface hydration and mitigate respiratory …

A central challenge in the progression of a variety of open questions in biology, such as
morphogenesis, wound healing, and development, is learning from empirical data how …

Nuclear reprogramming can change cellular fates. Yet, reprogramming efficiency is low and
the resulting cell types are often not functional. Here, we used nuclear transfer to eggs to …

Integration basally located progenitors into an existing epithelium is crucial for tissue
morphogenesis during embryogenesis and tissue homeostasis of epithelial organs. In this …

The lung is a vital organ in the body enabling us to breathe. During chronic lung diseases,
the function of the lung is impacted by damage to the tissue structure. Idiopathic pulmonary …

Generative AI and deep learning technologies have captured societal interest in recent
years due to their increasingly adaptive capabilities, but, we have yet to see similarly useful …