Non-Peptide Opioids Differ in Effects on Mu-Opioid (MOP) and Serotonin 1A (5-HT1A) Receptors Heterodimerization and Cellular Effectors (Ca2+, ERK1/2 and p38) …
V Radoi, G Jakobsson, V Palada, A Nikosjkov, H Druid… - Molecules, 2022 - mdpi.com
The importance of the dynamic interplay between the opioid and the serotonin
neuromodulatory systems in chronic pain is well recognized. In this study, we investigated …
neuromodulatory systems in chronic pain is well recognized. In this study, we investigated …
RNA‐Cleaving DNA Thresholder Controlled by Concentrations of miRNA Cancer Marker
AG Gomes de Oliveira, MV Dubovichenko… - …, 2021 - Wiley Online Library
Oligonucleotide gene therapy (OGT) agents suppress specific mRNAs in cells and thus
reduce the expression of targeted genes. The ability to unambiguously distinguish cancer …
reduce the expression of targeted genes. The ability to unambiguously distinguish cancer …
Signaling activations through G-protein-coupled-receptor aggregations
M Watabe, H Yoshimura, SNV Arjunan, K Kaizu… - Physical Review E, 2020 - APS
Eukaryotic cells transmit extracellular signal information to cellular interiors through the
formation of a ternary complex made up of a ligand (or agonist), G-protein, and G-protein …
formation of a ternary complex made up of a ligand (or agonist), G-protein, and G-protein …