Osteosarcoma, the most common malignant tumor of the bone, seriously influences people's
lives and increases their economic burden. Conventional chemotherapy drugs achieve …

A variety of targeted nanoparticles were developed for the diagnosis and therapy of
orthotopic and metastatic bone tumors during the past decade. This critical review will focus …

Bone diseases including osteoarthritis, osteoporosis, and bone tumors are becoming severe
threats to public health. Bone-targeted biomaterials-based strategies could improve …

Osteosarcoma (OSA) is a type of bone cancer that begins in the cells that form bones. OSA
is a rare mesenchymal bone neoplasm derived from mesenchymal stem cells. Genome …

Simple Summary Despite the adoption of aggressive, multimodal treatment schedules, the
cure rate of high-grade osteosarcoma (HGOS) has not significantly improved in the last 30 …

Osteosarcoma is the most common primary malignant bone tumor mainly occurred in
children and adolescence, and chemotherapy is limited for the side effects and development …

Drugs administered through conventional formulations are devoid of targeting and often
spread to various undesired sites, leading to sub-lethal concentrations at the site of action …

Although bone tissues possess an intrinsic capacity for repair, there are cases where bone
healing is either impaired or insufficient, such as fracture non-union, osteoporosis …

We report the thermodynamically controlled growth of solution-processable and free-
standing nanosheets via peptide assembly in two dimensions. By taking advantage of self …

The systemic administration of drugs to treat bone diseases is often associated with poor
uptake of the drug in the targeted tissue, potential systemic toxicity and suboptimal efficacy …