Purpose Genetic factors have a role in response to a target medication (personalized
medicine). This study aimed to review available evidence about the relationship between …

Background Type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) are two
deadly diseases caused by the complex interaction of multiple genetic loci, lifestyle and …

Due to the central role in insulin secretion, the potassium inwardly-rectifying channel
subfamily J member 11 (KCNJ11) gene is one of the essential genes for type 2 diabetes …

Background The genetic association studies of type 2 diabetes mellitus (T2DM) hitherto
undertaken among the Indian populations are grossly inadequate representation of the …

Abstract Background Population-based Genome-wide association studies showed variants
in KCNJ11 and TCF7L2 genes are associated with type 2 diabetes mellitus (T2DM). Our …

Methods: DNA was extracted from blood samples of 155 patients with T2D and 100 controls.
Genotyping was performed by polymerase chain reaction-restriction fragment length …

Background Potassium inwardly rectifying channel, subfamily J member 11 (KCNJ11) is
considered to be a potential susceptible gene of type 2 diabetes mellitus (T2DM), and the …

Background: Type 2 diabetes mellitus describes a metabolic disorder characterised by
prolonged elevated blood glucose that brings a risk of developing microvascular and …

目的Kir6. 2 编码基因多态与糖尿病, 胰岛素抵抗相关, 本研究旨在探讨高糖环境下,
利拉鲁肽对Kir6. 2 基因E23K 位点突变的胰岛β 细胞胰岛素分泌功能的影响及机制. 方法以NIT …

Type 2 diabetes mellitus (T2DM) is a common, lifelong metabolic disorder. Adults with T2DM
bear a greater burden of cardiometabolic risk factors than the general population. T2DM …