[HTML][HTML] Oxidation and Antioxidation of Natural Products in the Model Organism Caenorhabditis elegans

A Zhu, F Zheng, W Zhang, L Li, Y Li, H Hu, Y Wu… - Antioxidants, 2022 - mdpi.com
Natural products are small molecules naturally produced by multiple sources such as plants,
animals, fungi, bacteria and archaea. They exert both beneficial and detrimental effects by …

Well-known polypeptides of deer antler velvet with key actives: modern pharmacological advances

H Sun, D Xiao, W Liu, X Li, Z Lin, Y Li… - … Archives of Pharmacology, 2024 - Springer
Deer antler velvet, with kidney tonifying, promoting the production of essence and blood,
strengthening tendons and bones, not only has a thousand-year medicinal history but also …

Antioxidant and anti-aging activities of Laminaria japonica polysaccharide in Caenorhabditis elegans based on metabonomic analysis

N Li, Q Li, X He, X Gao, L Wu, M Xiao, W Cai… - International journal of …, 2022 - Elsevier
In this study, Laminaria japonica polysaccharide (LJP) was measured in vitro against three
antioxidant indicators: DPPH, ABTS, and hydroxyl. In vivo, LJP investigated thermal …

Anti-aging effects of the fermented anthocyanin extracts of purple sweet potato on Caenorhabditis elegans

J Zhao, J Yu, Q Zhi, T Yuan, X Lei, K Zeng, J Ming - Food & Function, 2021 - pubs.rsc.org
Anthocyanins have anti-inflammatory, anticarcinogenic and antioxidant properties and anti-
aging effects as well as potential application as pigments. The metabolism of anthocyanins …

[HTML][HTML] Ginsenoside Rd protects transgenic Caenorhabditis elegans from β-amyloid toxicity by activating oxidative resistant

L Mi, M Fan, T Liu, D Wu, Y Wang, F Li, Y Cai… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a serious public health issue but few drugs are currently
available for the disease, and these only target the symptoms. It is well established that …

[HTML][HTML] Chlorogenic acid of Cirsium japonicum resists oxidative stress caused by aging and prolongs healthspan via SKN-1/Nrf2 and DAF-16/FOXO in …

M Cho, Y Kim, S You, DY Hwang, M Jang - Metabolites, 2023 - mdpi.com
To evaluate the value of Cirsium japonicum (CJ; thistle) as a material for functional foods, we
studied the functional composition of cultivated CJ and the in vitro and in vivo antioxidant …

[HTML][HTML] Raspberry extract ameliorates oxidative stress in Caenorhabditis elegans via the SKN-1/Nrf2 pathway

B Song, B Zheng, T Li, RH Liu - Journal of Functional Foods, 2020 - Elsevier
Raspberries are rich in phytochemicals with health benefits. Our previous research has
shown raspberry extracts (RE) can promote longevity in Caenorhabditis elegans. The …

Effects of ethyl acetate fractional extract from Portulaca oleracea L. (PO‐EA) on lifespan and healthspan in Caenorhabditis elegans

W Zhang, B Zheng, N Deng, H Wang… - Journal of Food …, 2020 - Wiley Online Library
Abstract Portulaca oleracea L.(PO), with abundant natural bioactive phytochemicals, exhibits
potential bioactivities and pharmacological activities. However, the mechanisms of action of …

Peptidomic analysis of pilose antler and its inhibitory effect on triple-negative breast cancer at multiple sites

K Zheng, Q Li, D Lin, X Zong, X Luo, M Yang, X Yue… - Food & function, 2020 - pubs.rsc.org
Pilose antler (PA) is a traditional Chinese functional food that has been reported to inhibit
breast cancer; however, the specific substances that exert this effect and the underlying …

SKN-1 is involved in combination of apple peels and blueberry extracts synergistically protecting against oxidative stress in Caenorhabditis elegans

B Song, B Zheng, T Li, RH Liu - Food & function, 2020 - pubs.rsc.org
Increased consumption of fruits and vegetables is associated with reduced risk of age-
related functional declines and chronic diseases, primarily attributed to their bioactive …