Introduction: Multicomponent reactions (MCR) has been utilized to synthesize a vast range
of analogs belonging to diverse classes of heterocyclic compounds offering …

This review covers diastereo-and enantiodivergent catalyzed reactions in acyclic and cyclic
systems using metal complexes or organocatalysts. Among them, nucleophilic addition to …

Chiral spirooxindoles are privileged heterocyclic motifs, which are widely found in natural
alkaloids and pharmaceuticals. Moreover, the construction of chiral spiro-cyclic frameworks …

Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

Abstract The legacy of Gilbert Newton Lewis (1875–1946) pervades the lexicon of chemical
bonding and reactivity. The power of his concept of donor–acceptor bonding is evident in the …

Multicomponent reactions (MCRs), which are located between one‐and two‐component
and polymerization reactions, provide a number of valuable conceptual and synthetic …

Transformations of organonitriles play an important role in both the laboratory and industry
due to their well-recognized chemical versatility. In particular, in organic chemistry the …

Cyclizations of N-Acyliminium Ions | Chemical Reviews ACS ACS Publications C&EN CAS
Find my institution Log In Chemical Reviews ACS Publications. Most Trusted. Most Cited …

Four-membered monocyclic aza-heterocycles, 1 despite their indisputable importance as
bioactive compounds and pharmaceutical tools, have received by the chemical community …

We report practical methodology for the catalytic, asymmetric synthesis of β-lactams
resulting from the development of a catalyzed reaction of ketenes (or their derived …