Novel agents for the pharmacological treatment of alcohol use disorder

EM Burnette, SJ Nieto, EN Grodin, LR Meredith… - Drugs, 2022 - Springer
Alcohol use disorder (AUD) is a highly prevalent but severely under-treated disorder, with
only three widely-approved pharmacotherapies. Given that AUD is a very heterogeneous …

Substance abuse among older adults

A Kuerbis, P Sacco, DG Blazer… - Clinics in geriatric …, 2014 - geriatric.theclinics.com
The initial wave of the baby boom generation turned 65 years old in 2011, a generation that
comprises 30% of the total US population. 1 The size of this generation and their longer life …

Alcoholic liver disease

HK Seitz, R Bataller, H Cortez-Pinto, B Gao… - Nature reviews Disease …, 2018 - nature.com
Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …

Recent progress in the drug development targeting SARS-CoV-2 main protease as treatment for COVID-19

W Cui, K Yang, H Yang - Frontiers in molecular biosciences, 2020 - frontiersin.org
The sudden outbreak of 2019 novel coronavirus (2019-nCoV, later named SARS-CoV-2)
rapidly turned into an unprecedented pandemic of coronavirus disease 2019 (COVID-19) …

Meta‐analysis of naltrexone and acamprosate for treating alcohol use disorders: when are these medications most helpful?

NC Maisel, JC Blodgett, PL Wilbourne… - …, 2013 - Wiley Online Library
Aims Although debates over the efficacy of oral naltrexone and acamprosate in treating
alcohol use disorders tend to focus on their global efficacy relative to placebo or their …

Alcohol and public health

R Room, T Babor, J Rehm - The lancet, 2005 - thelancet.com
Alcoholic beverages, and the problems they engender, have been familiar fixtures in human
societies since the beginning of recorded history. We review advances in alcohol science in …

Opioid antagonists for alcohol dependence

S Roesner, A Hackl‐Herrwerth… - Cochrane database …, 2010 - cochranelibrary.com
Background Alcohol dependence belongs to the globally leading health risk factors.
Therapeutic success of psychosocial programs for relapse prevention is moderate and could …

Treatment and prevention of mental disorders in low-income and middle-income countries

V Patel, R Araya, S Chatterjee, D Chisholm, A Cohen… - The lancet, 2007 - thelancet.com
We review the evidence on effectiveness of interventions for the treatment and prevention of
selected mental disorders in low-income and middle-income countries. Depression can be …

[HTML][HTML] Systems to rate the strength of scientific evidence: summary

S West, V King, TS Carey, KN Lohr… - AHRQ evidence …, 2002 - ncbi.nlm.nih.gov
Health care decisions are increasingly being made on research-based evidence rather than
on expert opinion or clinical experience alone. Systematic reviews represent a rigorous …

Prevention, screening, and treatment for heavy drinking and alcohol use disorder

J Knox, DS Hasin, FRR Larson, HR Kranzler - The Lancet Psychiatry, 2019 - thelancet.com
Heavy drinking and alcohol use disorder are major public health problems. Practitioners not
specialising in alcohol treatment are often unaware of the guidelines for preventing …