This review summarizes the state-of-the-art in transition metal-catalyzed asymmetric
alkylation of heteroarenes using alkenes (covering literature from 2000 to late 2021). Based …

The Stetter reaction is actually a special C− C bond forming reaction through a 1, 4‐addition
reaction in the presence of nucleophilic catalyst. It involves a reaction between aldehydes …

The development of enantioconvergent cross‐coupling of racemic alkyl halides directly with
heteroarene C (sp2)− H bonds has been impeded by the use of a base at elevated …

Substituted and annulated pyrroles containing chiral centers are potentially accessible by
means of an organocatalytic enantioselective Friedel‐Crafts alkylation (FCA) reaction. They …

The wide occurrence of pyrroles in natural products and pharmaceuticals calls for novel
synthetic methodologies for the efficient synthesis of enantiopure pyrroles. Owing to their …

Abstract The first enantioselective Friedel‐Crafts (FC) allenylation reaction for the creation of
central chirality is developed under cooperative Ir (I)/(phosphoramidite, olefin) and Lewis …

The Mannich reaction is a multicomponent reaction resulting in aminoalkylation of an acidic
proton placed next to a carbonyl functional group. It involves an appropriate carbonyl …

Metal‐catalyzed asymmetric allylic substitution (AAS) reaction is one of the most
synthetically useful reactions catalyzed by metal complexes for the formation of carbon …

Comprehensive Summary The direct addition of aryl C—H bond to carbon‐heteroatom
double bond by transition‐metal‐catalyzed C—H activation has been extensively …

The development of chiral ligands to fine-tune stereocontrol in asymmetric catalysis is of
great demand. To diversify the Py-2NO ligand library recently developed by our group …