The functions, purposes, and roles of metallothioneins have been the subject of
speculations since the discovery of the protein over 60 years ago. This article guides …

After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential
for the function of the immune system. Zinc ions are involved in regulating intracellular …

Wound care is a major healthcare expenditure. Treatment of burns, surgical and trauma
wounds, diabetic lower limb ulcers and skin wounds is a major medical challenge with …

Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic
homeostasis of this essential trace element. This review summarizes the key aspects of …

Metal ions are essential for many reactions, but excess metals can be toxic. In bacteria,
metal limitation activates pathways that are involved in the import and mobilization of metals …

The solution and complexation chemistry of zinc ions is the basis for zinc biology. In living
organisms, zinc is redox-inert and has only one valence state: Zn (II). Its coordination …

Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Small-molecule fluorescent probes are attractive and versatile materials for studying
biological systems.(1-6) They can be easily loaded into cells and rapidly detect biological …

In the last decade, we witnessed discoveries that established Zn2+ as a second major
signalling metal ion in the transmission of information within cells and in communication …

During the last few decades, the micronutrient zinc has proven to be an important metal ion
for a well-functioning immune system, and thus also for a suitable immune defense …