Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application

X Zhao, J Liu, J Fan, H Chao, X Peng - Chemical Society Reviews, 2021 - pubs.rsc.org
Photodynamic therapy (PDT), a therapeutic mode involving light triggering, has been
recognized as an attractive oncotherapy treatment. However, nonnegligible challenges …

Type I AIE photosensitizers: Mechanism and application

J Li, Z Zhuang, Z Zhao, BZ Tang - View, 2022 - Wiley Online Library
Photodynamic therapy (PDT) with plenty of advantages is expected to become a promising
modality for cancer treatment, but challenges still remain. In the past decade, abundant …

GSH and H2O2 Co‐Activatable Mitochondria‐Targeted Photodynamic Therapy under Normoxia and Hypoxia

J Sun, K Du, J Diao, X Cai, F Feng… - Angewandte …, 2020 - Wiley Online Library
Currently, photosensitizers (PSs) that are microenvironment responsive and hypoxia active
are scarcely available and urgently desired for antitumor photodynamic therapy (PDT) …

Enhanced photodynamic therapy for overcoming tumor hypoxia: From microenvironment regulation to photosensitizer innovation

J Du, T Shi, S Long, P Chen, W Sun, J Fan… - Coordination Chemistry …, 2021 - Elsevier
Photodynamic therapy (PDT) has garnered an increasing interest by both researchers and
clinicians as a non-invasive therapy that allows a selective treatment towards tumors …

Self‐Immolative Amphiphilic Poly (ferrocenes) for Synergistic Amplification of Oxidative Stress in Tumor Therapy

J Xu, J Tan, C Song, G Zhang, X Hu… - Angewandte Chemie, 2023 - Wiley Online Library
Amphiphilic self‐immolative polymers (SIPs) can achieve complete degradation solely
through one triggerable event, which potentially optimize the blood clearance and …

Type I photodynamic antimicrobial therapy: Principles, progress, and future perspectives

J Jiang, X Lv, H Cheng, D Yang, W Xu, Y Hu, Y Song… - Acta Biomaterialia, 2024 - Elsevier
The emergence of drug-resistant bacteria has significantly diminished the efficacy of existing
antibiotics in the treatment of bacterial infections. Consequently, the need for finding a …

Nitrogen-doped carbon dots as a highly efficient photosensitizer for photodynamic therapy to promote apoptosis in oral squamous cell carcinoma

L Sun, Y Zhao, J Yan, J Wang, H Cheng… - Colloids and Surfaces A …, 2024 - Elsevier
Photodynamic (PDT) is a new strategy for non-invasive tumor therapy and has been studied
for the treatment of oral cancer. PDT has the advantages of low damage and high …

Delayed Fluorescence Materials: Mechanism, Design, and Bioapplication

L Zhu, Z Zhang, Y Liu, Z Deng, Y Luo… - The Journal of …, 2024 - ACS Publications
Materials with delayed fluorescence (DF) are characterized by an available triplet state and
prolonged fluorescence lifetime. In particular, those thermally activated delayed …

Multifunctional Molecular Hybrids Photoreleasing Nitric Oxide: Advantages, Pitfalls, and Opportunities

C Parisi, F Laneri, A Fraix, S Sortino - Journal of Medicinal …, 2024 - ACS Publications
The multifaceted role nitric oxide (NO) plays in human physiology and pathophysiology has
opened new scenarios in biomedicine by exploiting this free radical as an unconventional …