Non-small cell lung cancer (NSCLC), which represents 80–85% of lung cancer cases, is one
of the leading causes of human death worldwide. The majority of patients undergo an …

Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …

Chemoresistance is a disturbing barrier in cancer therapy, which always results in limited
therapeutic options and unfavorable prognosis. Nuclear factor E2-related factor 2 (NRF2) …

Advanced non-small cell lung cancer (NSCLC) continues to be an incurable family of
thoracic malignancies that is chronically managed with chemotherapy, targeted therapy, and …

Resistance to the hypomethylating agents (HMAs) 5-azacytidine (AZA) and 5-aza-2′-
deoxycytidine (DAC) represents a major obstacle in the treatment of elderly patients with …

Cepharanthine, a natural bisbenzylisoquinoline (BBIQ) alkaloid isolated from the plant
Stephania Cephalantha Hayata, is the only bisbenzylisoquinoline alkaloid approved for …

Chemotherapy is widely used for cancer treatment, but its effectiveness is limited by drug
resistance. Here, we report a mechanism by which cell density activates the Hippo pathway …

Ethnopharmacological relevance: Artemisia argyi H. Lév. & Vaniot (Asteraceae), also called
“Chinese mugwort”, is frequently used as a herbal medicine in China, Japan, Korea, and …

Degradable polymer prodrugs based on gemcitabine (Gem) as an anticancer drug were
synthesized by 'drug-initiated'nitroxide-mediated radical ring-opening copolymerization …

Chemoresistance is a major problem in the therapeutic management of pancreatic cancer,
concurring to poor clinical outcome. A number of mechanisms have been proposed to …