Pyoderma gangrenosum: an updated literature review on established and emerging pharmacological treatments

CA Maronese, MA Pimentel, MM Li… - American Journal of …, 2022 - Springer
Pyoderma gangrenosum is a rare inflammatory skin disease classified within the group of
neutrophilic dermatoses and clinically characterized by painful, rapidly evolving cutaneous …

Pyoderma gangrenosum

E Maverakis, AV Marzano, ST Le, JP Callen… - Nature Reviews …, 2020 - nature.com
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis that presents with rapidly
developing, painful skin ulcers hallmarked by undermined borders and peripheral erythema …

Pyoderma gangrenosum: an update on pathophysiology, diagnosis and treatment

A Alavi, LE French, MD Davis, A Brassard… - American journal of …, 2017 - Springer
Pyoderma gangrenosum (PG) is a rare inflammatory neutrophilic disorder with prototypical
clinical presentations. Its pathophysiology is complex and not fully explained. Recent …

Pathophysiology of pyoderma gangrenosum (PG): an updated review

SF Braswell, TC Kostopoulos… - Journal of the American …, 2015 - Elsevier
Pyoderma gangrenosum is a challenging skin condition to identify and treat because of its
multifactorial pathogenesis. It is a rare cutaneous manifestation diagnosed clinically by …

A comprehensive review of neutrophilic diseases

AV Marzano, A Borghi, D Wallach, M Cugno - Clinical reviews in allergy & …, 2018 - Springer
Neutrophilic dermatoses are a group of conditions characterized by the accumulation of
neutrophils in the skin and clinically presenting with polymorphic cutaneous lesions …

Autoinflammation in pyoderma gangrenosum and its syndromic form (pyoderma gangrenosum, acne and suppurative hidradenitis)

AV Marzano, G Damiani, I Ceccherini… - British Journal of …, 2017 - academic.oup.com
Background Pyoderma gangrenosum (PG) is a rare skin disease characterized clinically by
ulcers with undermined borders, and histologically by neutrophil‐rich infiltrates. PG may …

The genetics of pyoderma gangrenosum and implications for treatment: a systematic review

EM DeFilippis, SR Feldman… - British Journal of …, 2015 - academic.oup.com
Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis characterized by painful skin
ulcerations for which treatment can be challenging. The genetic basis of PG may provide a …

Pyoderma gangrenosum: A systematic review of the molecular characteristics of disease

A Flora, E Kozera, JW Frew - Experimental Dermatology, 2022 - Wiley Online Library
Pyoderma gangrenosum is a painful recurrent ulcerative neutrophilic dermatosis in which
the pathogenesis is incompletely defined. Current evidence suggests that PG is associated …

Pyoderma gangrenosum in hematologic malignancies: a systematic review

CM Montagnon, EA Fracica, AA Patel… - Journal of the American …, 2020 - Elsevier
Background Pyoderma gangrenosum (PG) is a devastating neutrophilic dermatosis that may
be associated with trauma or systemic diseases. The associations, characteristics, and …

Tofacitinib for the treatment of refractory pyoderma gangrenosum

VE Orfaly, I Kovalenko, SN Tolkachjov… - Clinical and …, 2021 - academic.oup.com
Pyoderma gangrenosum (PG) is a rare, debilitating, inflammatory skin disease associated
with a variety of systemic diseases. Because of its rarity, PG is treated with miscellaneous …