Programmed cell death pathways and current antitumor targets
Apoptosis and autophagic cell deaths are programmed cell deaths and they play essential
roles in cell survival, growth and development and tumorigenesis. The huge increase of …
roles in cell survival, growth and development and tumorigenesis. The huge increase of …
Cytoprotective effect of the elongation factor-2 kinase-mediated autophagy in breast cancer cells subjected to growth factor inhibition
Y Cheng, H Li, X Ren, T Niu, WN Hait, J Yang - PLoS One, 2010 - journals.plos.org
Background Autophagy is a highly conserved and regulated cellular process employed by
living cells to degrade proteins and organelles as a response to metabolic stress. We have …
living cells to degrade proteins and organelles as a response to metabolic stress. We have …
Arsenic salts induced autophagic cell death and hypermethylation of DAPK promoter in SV-40 immortalized human uroepithelial cells
CY Chai, YC Huang, WC Hung, WY Kang, WT Chen - Toxicology letters, 2007 - Elsevier
Arsenic is a well-known toxic and carcinogenic agent, and associated with various human
malignancies, including skin, lung and bladder cancers. Paradoxically, arsenic trioxide has …
malignancies, including skin, lung and bladder cancers. Paradoxically, arsenic trioxide has …
Immunohistochemical expression of MAP1LC3A and MAP1LC3B protein in breast carcinoma tissues
Autophagy is a protein degradation process within the cell and its deregulation has been
linked to various diseases and the formation of cancer. One of the important proteins …
linked to various diseases and the formation of cancer. One of the important proteins …
para-Phenylenediamine-induced autophagy in human uroepithelial cell line mediated mutant p53 and activation of ERK signaling pathway
YC Huang, WC Hung, SM Chye, WT Chen, CY Chai - Toxicology in Vitro, 2011 - Elsevier
para-Phenylenediamine (p-PD) is a major aromatic amine that is a widely used commercial
oxidative-type hair dye. Some epidemiologic studies have suggested that the use of p-PD …
oxidative-type hair dye. Some epidemiologic studies have suggested that the use of p-PD …