Host defense antimicrobial peptides as antibiotics: design and application strategies

B Mishra, S Reiling, D Zarena, G Wang - Current opinion in chemical …, 2017 - Elsevier
Highlights•Antibiotic resistance is a serious problem of our era.•Antimicrobial peptides are
important templates for developing new antibiotics.•Both peptide discovery and application …

Molecular mechanisms of antiviral agents against dengue virus

MF Lee, YS Wu, CL Poh - Viruses, 2023 - mdpi.com
Dengue is a major global health threat causing 390 million dengue infections and 25,000
deaths annually. The lack of efficacy of the licensed Dengvaxia vaccine and the absence of …

[HTML][HTML] Peptides as therapeutic agents for dengue virus

MF Chew, KS Poh, CL Poh - International journal of medical …, 2017 - ncbi.nlm.nih.gov
Dengue is an important global threat caused by dengue virus (DENV) that records an
estimated 390 million infections annually. Despite the availability of CYD-TDV as a …

Peptides targeting dengue viral nonstructural protein 1 inhibit dengue virus production

P Songprakhon, T Thaingtamtanha, T Limjindaporn… - Scientific Reports, 2020 - nature.com
Viruses manipulate the life cycle in host cells via the use of viral properties and host
machineries. Development of antiviral peptides against dengue virus (DENV) infection has …

Discovery of antivirals using phage display

E Sokullu, MS Gauthier, B Coulombe - Viruses, 2021 - mdpi.com
The latest coronavirus disease outbreak, COVID-19, has brought attention to viral infections
which have posed serious health threats to humankind throughout history. The rapid global …

[PDF][PDF] Antiviral activity of copper (II) chloride dihydrate against dengue virus type-2 in vero cell

TH Sucipto, S Churrotin, H Setyawati… - … Journal of Tropical …, 2017 - e-journal.unair.ac.id
Infection of dengue virus (DENV) was number of globally significant emerging pathogen.
Antiviral dengue therapies are importantly needed to control emerging dengue. Dengue …

New copper (II)-imidazole derivative effectively inhibits replication of DENV-2 in Vero cell

TH Sucipto, S Churrotin, H Setyawati, F Martak… - African Journal of …, 2018 - ajol.info
Background: Dengue is a kind of infectious disease that was distributed in the tropical and
sub-tropical areas. To date, there is no clinically approved dengue vaccine or antiviral for …

Stability and antiviral activity of SP40 peptide in human serum

F Zarif, MI Anasir, JX Koh, MF Chew, CL Poh - Virus Research, 2021 - Elsevier
Abstract Enterovirus A71 (EV-A71) is one of the main causative agents of hand, foot and
mouth disease (HFMD). SP40 peptide was previously identified to inhibit EV-A71 strains …

[HTML][HTML] Anti-DENV-2 Activity of Ethanolic Extracts from Arachis hypogaea L.: Peanut Skin as a Relevant Resource of Bioactive Compounds against Dengue Virus

F Menis Candela, EA Soria, MV Moliva… - Plants, 2024 - mdpi.com
Dengue is an emerging disease of high impact on human health. Plants are an important
source of new antivirals and Arachis hypogaea stands for its biological properties. The aim …

Phage‐Displayed Peptides Selected to Bind Envelope Glycoprotein Show Antiviral Activity against Dengue Virus Serotype 2

C de la Guardia, M Quijada, R Lleonart - Advances in Virology, 2017 - Wiley Online Library
Dengue virus is a growing public health threat that affects hundreds of million peoples every
year and leave huge economic and social damage. The virus is transmitted by mosquitoes …