Review of the immune checkpoint inhibitors in the context of cancer treatment

NA Alturki - Journal of Clinical Medicine, 2023 - mdpi.com
Checkpoint proteins are an integral part of the immune system and are used by the tumor
cells to evade immune response, which helps them grow uncontrollably. By blocking these …

The association between albumin levels and survival in patients treated with immune checkpoint inhibitors: A systematic review and meta-analysis

DC Guven, TK Sahin, E Erul, A Rizzo… - Frontiers in Molecular …, 2022 - frontiersin.org
Background: The albumin levels may potentially be used as a prognostic biomarker in
patients with cancertreated with immune checkpoint inhibitors (ICIs) due to its close …

Neoadjuvant immunotherapy and chemoimmunotherapy for stage II-III muscle invasive bladder cancer

H Chen, W Yang, X Xue, Y Li, Z Jin, Z Ji - Frontiers in Immunology, 2022 - frontiersin.org
Objective Considering the striking evidence revealed by immunotherapy in advanced or
metastatic bladder cancer, investigators have explored neoadjuvant immunotherapy and …

Pretreatment clinical and hematologic prognostic factors of metastatic urothelial carcinoma treated with pembrolizumab: a systematic review and meta-analysis

T Yanagisawa, K Mori, S Katayama… - International Journal of …, 2022 - Springer
Pembrolizumab is the standard for the first and second lines in treating metastatic urothelial
carcinoma (UC). This systematic review and meta-analysis aimed to assess the value of …

Japanese subgroup analysis of EV‐301: an open‐label, randomized phase 3 study to evaluate enfortumab vedotin versus chemotherapy in subjects with previously …

N Matsubara, J Yonese, T Kojima, H Azuma… - Cancer …, 2023 - Wiley Online Library
Background Enfortumab vedotin (EV) is an antibody‐drug conjugate showing significant
overall survival (OS) benefit versus chemotherapy for patients with previously treated locally …

Impact of sex on the efficacy of immune checkpoint inhibitors in kidney and urothelial cancers: a systematic review and meta-analysis

T Yanagisawa, T Kawada, F Quhal, K Bekku… - World Journal of …, 2023 - Springer
Purpose To analyze and summarize the efficacy of immune checkpoint inhibitor (ICI) alone
or in combination therapy for renal cell carcinoma (RCC) and urothelial carcinoma (UC) …

[HTML][HTML] The effect of immune checkpoint inhibitor combination therapies in metastatic renal cell carcinoma patients with and without previous cytoreductive …

K Mori, F Quhal, T Yanagisawa, S Katayama… - International …, 2022 - Elsevier
Background Recently, immune checkpoint inhibitor (ICI)-combination therapies have
radically altered the treatment landscape in metastatic renal cell carcinoma (mRCC). No …

[HTML][HTML] Reassessment of the efficacy of carboplatin for metastatic urothelial carcinoma in the era of immunotherapy: a systematic review and meta-analysis

K Mori, VM Schuettfort, T Yanagisawa… - European Urology …, 2022 - Elsevier
Context Platinum-based combination chemotherapy is the standard treatment for advanced
or metastatic urothelial carcinoma (AMUC). However, data comparing the efficacy of different …

Prognostic and predictive factors in advanced urothelial carcinoma treated with immune checkpoint inhibitors: A review of the current evidence

SE Rebuzzi, GL Banna, V Murianni, A Damassi… - Cancers, 2021 - mdpi.com
Simple Summary Despite immune checkpoint inhibitors'(ICIs) improved overall survival in
urothelial carcinoma patients, only a minority of them benefit from immunotherapy …

Adverse effects and toxicity of immune checkpoint inhibitors for patients with urothelial carcinoma

D Wang, K Sun, T Wang, D Zhang, F Sun… - Frontiers in …, 2021 - frontiersin.org
Urothelial carcinoma (UC) occupies a high incidence among all the genitourinary
malignancies. Immune checkpoint inhibitors (ICIs), as alternative treatments of metastatic …