Tfos dews ii pathophysiology report

AJ Bron, CS de Paiva, SK Chauhan, S Bonini… - The ocular …, 2017 - Elsevier
Abstract The TFOS DEWS II Pathophysiology Subcommittee reviewed the mechanisms
involved in the initiation and perpetuation of dry eye disease. Its central mechanism is …

Corneal nerves in health and disease

BS Shaheen, M Bakir, S Jain - Survey of ophthalmology, 2014 - Elsevier
Corneal nerves are responsible for the sensations of touch, pain, and temperature and play
an important role in the blink reflex, wound healing, and tear production and secretion …

[图书][B] Swine in the laboratory: surgery, anesthesia, imaging, and experimental techniques

MM Swindle - 2007 - taylorfrancis.com
To diminish the learning curve associated with using swine as models, Swine in the
Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition …

Modelling the complexity of human skin in vitro

E Hofmann, A Schwarz, J Fink, LP Kamolz, P Kotzbeck - Biomedicines, 2023 - mdpi.com
The skin serves as an important barrier protecting the body from physical, chemical and
pathogenic hazards as well as regulating the bi-directional transport of water, ions and …

Single-cell transcriptomics identifies limbal stem cell population and cell types mapping its differentiation trajectory in limbal basal epithelium of human cornea

DQ Li, S Kim, JM Li, Q Gao, J Choi, F Bian, J Hu… - The ocular …, 2021 - Elsevier
Purpose This study aimed to uncover novel cell types in heterogenous basal limbus of
human cornea for identifying LSC at single cell resolution. Methods Single cells of human …

In vivo confocal microscopy as a novel and reliable tool for the diagnosis of Demodex eyelid infestation

M Randon, H Liang, M El Hamdaoui, R Tahiri… - British Journal of …, 2015 - bjo.bmj.com
Aims Demodex mites are implicated in several ocular surface diseases such as blepharitis,
ocular rosacea and dry eye syndrome. Demodex eyelid infestation is classically diagnosed …

Mechanical tension mobilizes Lgr6+ epidermal stem cells to drive skin growth

Y Xue, C Lyu, A Taylor, A Van Ee, A Kiemen… - Science …, 2022 - science.org
Uniquely among mammalian organs, skin is capable of marked size change in adults, yet
the mechanisms underlying this notable capacity are unclear. Here, we use a system of …

[HTML][HTML] Spdef null mice lack conjunctival goblet cells and provide a model of dry eye

CK Marko, BB Menon, G Chen, JA Whitsett… - The American journal of …, 2013 - Elsevier
Goblet cell numbers decrease within the conjunctival epithelium in drying and cicatrizing
ocular surface diseases. Factors regulating goblet cell differentiation in conjunctival …

[HTML][HTML] Comparison of tear proteomic and neuromediator profiles changes between small incision lenticule extraction (SMILE) and femtosecond laser-assisted in-situ …

YC Liu, GHF Yam, MTY Lin, E Teo, SK Koh… - Journal of Advanced …, 2021 - Elsevier
Introduction The tear proteomics and neuromediators are associated with clinical dry eye
parameters following refractive surgery. Purpose To investigate and compare the tear …

Interferons and dry eye in Sjögren's syndrome

Y Ogawa, E Shimizu, K Tsubota - International journal of molecular …, 2018 - mdpi.com
Various cytokines, including interferon (IFN)-γ and IL-17, are augmented, and autoreactive T
cells and B cells are activated in the immune pathogenesis of Sjögren's syndrome (SS). In …