Biomarkers associated with COVID-19 disease progression

G Ponti, M Maccaferri, C Ruini, A Tomasi… - Critical reviews in …, 2020 - Taylor & Francis
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a scientific, medical, and
social challenge. The complexity of the severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] Platelets in sepsis: an update on experimental models and clinical data

A Assinger, WC Schrottmaier, M Salzmann… - Frontiers in …, 2019 - frontiersin.org
Beyond their important role in hemostasis, platelets play a crucial role in inflammatory
diseases. This becomes apparent during sepsis, where platelet count and activation …

Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis

G Lippi, M Plebani, BM Henry - Clinica chimica acta, 2020 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19) is a novel infectious disease
with lack of established laboratory markers available to evaluate illness severity. In this …

Platelets are critical key players in sepsis

F Vardon-Bounes, S Ruiz, MP Gratacap… - International journal of …, 2019 - mdpi.com
Host defense against infection is based on two crucial mechanisms: the inflammatory
response and the activation of coagulation. Platelets are involved in both hemostasis and …

Association between platelet parameters and mortality in coronavirus disease 2019: Retrospective cohort study

Y Liu, W Sun, Y Guo, L Chen, L Zhang, S Zhao, D Long… - Platelets, 2020 - Taylor & Francis
Background Thrombocytopenia has been implicated in patients infected with severe acute
respiratory syndrome coronavirus 2, while the association of platelet count and changes with …

Platelets: bridging hemostasis, inflammation, and immunity

CN Jenne, R Urrutia, P Kubes - International journal of …, 2013 - Wiley Online Library
Although the function of platelets in the maintenance of hemostasis has been studied in
great detail, more recent evidence has highlighted a central role for platelets in the host …

Blood platelets and sepsis pathophysiology: a new therapeutic prospect in critical ill patients?

A Dewitte, S Lepreux, J Villeneuve, C Rigothier… - Annals of intensive …, 2017 - Springer
Beyond haemostasis, platelets have emerged as versatile effectors of the immune response.
The contribution of platelets in inflammation, tissue integrity and defence against infections …

Platelets in pulmonary immune responses and inflammatory lung diseases

EA Middleton, AS Weyrich… - Physiological …, 2016 - journals.physiology.org
Platelets are essential for physiological hemostasis and are central in pathological
thrombosis. These are their traditional and best known activities in health and disease. In …

Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes

DR Williamson, M Albert, D Heels-Ansdell, DM Arnold… - Chest, 2013 - Elsevier
Background Thrombocytopenia is the most common hemostatic disorder in critically ill
patients. The objective of this study was to describe the incidence, risk factors, and outcomes …

How to approach thrombocytopenia

R Stasi - Hematology 2010, the American Society of …, 2012 - ashpublications.org
Thrombocytopenia is a common hematologic finding with variable clinical expression. A low
platelet count may be the initial manifestation of infections such as HIV and hepatitis C virus …