Cholesterol transport system: an integrated cholesterol transport model involved in atherosclerosis

XH Yu, DW Zhang, XL Zheng, CK Tang - Progress in Lipid Research, 2019 - Elsevier
Atherosclerosis, the pathological basis of most cardiovascular disease (CVD), is closely
associated with cholesterol accumulation in the arterial intima. Excessive cholesterol is …

High-density lipoproteins: a consensus statement from the National Lipid Association

PP Toth, PJ Barter, RS Rosenson, WE Boden… - Journal of clinical …, 2013 - Elsevier
For> 4 decades it has been recognized that elevated serum levels of high-density
lipoprotein cholesterol (HDL-C) are associated with reduced risk of cardiovascular disease …

HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events

RS Rosenson, HB Brewer Jr, MJ Chapman… - Clinical …, 2011 - academic.oup.com
BACKGROUND A growing body of evidence from epidemiological data, animal studies, and
clinical trials supports HDL as the next target to reduce residual cardiovascular risk in statin …

Atherogenic dyslipidemia: cardiovascular risk and dietary intervention

K Musunuru - Lipids, 2010 - Springer
Atherogenic dyslipidemia comprises a triad of increased blood concentrations of small,
dense low-density lipoprotein (LDL) particles, decreased high-density lipoprotein (HDL) …

Endothelial and antithrombotic actions of HDL

C Mineo, H Deguchi, JH Griffin, PW Shaul - Circulation research, 2006 - Am Heart Assoc
It is well recognized that high-density lipoprotein (HDL)-cholesterol is antiatherogenic and
serves a role in mediating cholesterol efflux from cells. However, HDL has multiple …

The apoB/apoA‐I ratio: a strong, new risk factor for cardiovascular disease and a target for lipid‐lowering therapy–a review of the evidence

G Walldius, I Jungner - Journal of internal medicine, 2006 - Wiley Online Library
During the last several years interest has focused on the importance of the lipid‐transporting
apolipoproteins–apoB transports all potentially atherogenic very low‐density lipoprotein …

The ability to promote efflux via ABCA1 determines the capacity of serum specimens with similar high-density lipoprotein cholesterol to remove cholesterol from …

M de la Llera-Moya, D Drazul-Schrader… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—We measured efflux from macrophages to apolipoprotein B-depleted serum from
263 specimens and found instances in which serum having similar high-density lipoprotein …

High-density lipoprotein as a therapeutic target: a systematic review

IM Singh, MH Shishehbor, BJ Ansell - Jama, 2007 - jamanetwork.com
ContextHigh-density lipoprotein cholesterol (HDL-C) is a cardiovascular risk factor that is
gaining substantial interest as a therapeutic target. ObjectivesTo review the current and …

Cholesterol esterification and atherogenic index of plasma correlate with lipoprotein size and findings on coronary angiography

M Dobiášová, J Frohlich, M Šedová, MC Cheung… - Journal of lipid …, 2011 - ASBMB
We examined the association between rate of cholesterol esterification in plasma depleted
of apolipoprotein B-containing lipoproteins (FER HDL), atherogenic index of plasma …

HDL particle number and size as predictors of cardiovascular disease

A Kontush - Frontiers in pharmacology, 2015 - frontiersin.org
Previous studies indicate that reduced concentrations of circulating high-density lipoprotein
(HDL) particles can be superior to HDL-cholesterol (HDL-C) levels as a predictor of …