Cancer is a multistep process that begins with the transformation of normal epithelial cells
and continues with tumor growth, stromal invasion and metastasis. The remodeling of the …

The prostate comprises a glandular epithelium embedded within a fibromuscular stroma.
The stroma is a complex arrangement of cells and extracellular matrix (ECM) components in …

Abstract Knowledge of structural and physiological differences among the prostatic lobes
(PL) is the basis for development of experimental studies in traditional laboratory rodents …

The prostate undergoes normal or pathological morphological changes throughout life. An
understanding of these changes is fundamental for the comprehension of aging‐related …

Summary The Meriones unguiculatus (Mongolian) gerbil has demonstrated significant
prostatic responses to hormonal treatments, and to drugs against human prostatic …

O sistema endócrino é uma complexa rede de glândulas e hormônios que regulam muitas
das funções do corpo, incluindo crescimento, desenvolvimento e maturação, como as vias …

The effect of oestradiol on the intact and castrated adult gerbil prostate was evaluated by
focussing on stromal and epithelial disorders, and hormonal receptor immunoreactivity. The …

BACKGROUND Characterization of novel rodent models for prostate cancer studies
requires evaluation of either spontaneous and carcinogen‐induced tumors as well as tumor …

The female organs, which are regulated by steroid hormones, are targets of studies
especially those related to senescence. However, although the female prostate is an organ …

Different from the classic view, the prostate is not a gland exclusive to the male, also being
an organ of the female genital system presenting morphofunctional similarity between …