Selenium, selenoproteins, and immunity

JC Avery, PR Hoffmann - Nutrients, 2018 - mdpi.com
Selenium is an essential micronutrient that plays a crucial role in development and a wide
variety of physiological processes including effect immune responses. The immune system …

Selenoproteins—what unique properties can arise with selenocysteine in place of cysteine?

ESJ Arnér - Experimental cell research, 2010 - Elsevier
The defining entity of a selenoprotein is the inclusion of at least one selenocysteine (Sec)
residue in its sequence. Sec, the 21st naturally occurring genetically encoded amino acid …

Expanding the Genetic Code of Escherichia coli with Phosphoserine

HS Park, MJ Hohn, T Umehara, LT Guo, EM Osborne… - Science, 2011 - science.org
O-Phosphoserine (Sep), the most abundant phosphoamino acid in the eukaryotic
phosphoproteome, is not encoded in the genetic code, but synthesized posttranslationally …

Selenium: From fluorescent probes to biomedical application

J Wang, M Chen, Z Zhang, L Ma, T Chen - Coordination Chemistry Reviews, 2023 - Elsevier
Selenium (Se) is of fundamental importance to human health as an essential trace element,
mainly through regulation of selenoproteins (SePs). Therefore, monitoring Se transformation …

Catalysis of peroxide reduction by fast reacting protein thiols: focus review

A Zeida, M Trujillo, G Ferrer-Sueta, A Denicola… - Chemical …, 2019 - ACS Publications
Life on Earth evolved in the presence of hydrogen peroxide, and other peroxides also
emerged before and with the rise of aerobic metabolism. They were considered only as toxic …

[HTML][HTML] Asgard archaea: diversity, function, and evolutionary implications in a range of microbiomes

F MacLeod, GS Kindler, HL Wong, R Chen… - AIMS …, 2019 - ncbi.nlm.nih.gov
Elucidating the diversity of the Archaea has many important ecological and evolutionary
implications. The Asgard superphylum of the archaea, described recently from metagenomic …

Genetic code flexibility in microorganisms: novel mechanisms and impact on physiology

J Ling, P O'donoghue, D Söll - Nature Reviews Microbiology, 2015 - nature.com
The genetic code, initially thought to be universal and immutable, is now known to contain
many variations, including biased codon usage, codon reassignment, ambiguous decoding …

[NiFeSe]-hydrogenase chemistry

C Wombwell, CA Caputo, E Reisner - Accounts of Chemical …, 2015 - ACS Publications
Conspectus The development of technology for the inexpensive generation of the
renewable energy vector H2 through water splitting is of immediate economic, ecological …

Predicting the Minimal Translation Apparatus: Lessons from the Reductive Evolution of Mollicutes

H Grosjean, M Breton, P Sirand-Pugnet, F Tardy… - PLoS …, 2014 - journals.plos.org
Mollicutes is a class of parasitic bacteria that have evolved from a common Firmicutes
ancestor mostly by massive genome reduction. With genomes under 1 Mbp in size, most …

Selenium—more than just a fortuitous sulfur substitute in redox biology

LB Maia, BK Maiti, I Moura, JJG Moura - Molecules, 2023 - mdpi.com
Living organisms use selenium mainly in the form of selenocysteine in the active site of
oxidoreductases. Here, selenium's unique chemistry is believed to modulate the reaction …