Macroautophagy/autophagy is a highly conserved evolutionary mechanism that involves
lysosomes for the degradation of cytoplasmic components including organelles. The …

Colorectal cancer (CRC) remains one of the major causes of cancer death worldwide.
Chemotherapy continues to serve as the primary treatment modality, while immunotherapy …

The 5-year survival rate for hepatocellular carcinoma (HCC), a deadly form of liver cancer, is
quite low. Although drug therapy is successful, patients with advanced liver cancer …

Autophagy is an intracellular degradation process that sequesters cytoplasmic components
in double-membrane vesicles known as autophagosomes, which are degraded upon fusion …

Autophagy is a self-digestion multistep process in which causes the homeostasis through
degradation of macromolecules and damaged organelles. The autophagy-mediated tumor …

Autophagy is an essential lysosome-mediated degradation pathway that maintains cellular
homeostasis and viability in response to various intra-and extracellular stresses. Mitophagy …

Circular RNAs (circRNAs) lack the 5'-end methylated guanine cap structure and
3'polyadenylate tail structure, classifying it as a non-coding RNA. With the extensive …

Aberrant signaling through damage-associated molecular patterns (DAMPs) has been
linked to several health disorders, attracting considerable research interest over the last …

The integrative multiomics characterization of minute amounts of clinical tissue specimens
has become increasingly important. Here, we present an approach called Integral-Omics …

Impaired autophagy is reported to promote osteoarthritis (OA). However, the mechanism by
which autophagy in regulating meniscus degeneration and OA remains unclear. Here …