Antibody modulation of B cell responses—Incorporating positive and negative feedback

JG Cyster, PC Wilson - Immunity, 2024 - cell.com
Antibodies are powerful modulators of ongoing and future B cell responses. While the
concept of antibody feedback has been appreciated for over a century, the topic has seen a …

Are we getting closer to a successful neoantigen cancer vaccine?

K Manoutcharian, G Gevorkian - Molecular Aspects of Medicine, 2024 - Elsevier
Although significant advances in immunotherapy have revolutionized the treatment of many
cancer types over the past decade, the field of vaccine therapy, an important component of …

Intra‐lymph node crosslinking of antigen‐bearing polymers enhances humoral immunity and dendritic cell activation

EM Euliano, A Agrawal, MH Yu, TP Graf… - Bioengineering & …, 2024 - Wiley Online Library
Lymph node (LN)‐resident dendritic cells (DCs) are a promising target for vaccination given
their professional antigen‐presenting capabilities and proximity to a high concentration of …

Immunoengineering a Future of Molecular, Material, and Cellular Therapeutics

JA Hubbell - The Journal of Immunology, 2024 - journals.aai.org
The interface between immunology and engineering, that is, immunoengineering, is
becoming fertile ground for innovation. Engineering comes into play when basic science has …