Introduction: Leishmaniasis is a vector-borne neglected tropical disease which manifests as
visceral leishmaniasis (VL), cutaneous leishmaniasis (CL), and mucocutaneous …

Antimicrobial treatment failure threatens our ability to control infections. In addition to
antimicrobial resistance, treatment failures are increasingly understood to derive from cells …

Protozoan parasites of the Leishmania donovani complex–L. donovani and L. infantum–
cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome …

For the past 15 years, trials of combination therapy options for visceral leishmaniasis have
been conducted with the aim of identifying effective, and safe treatment regimens that were …

This mini-review focuses on leishmanicidal drugs that were sourced from small molecules
previously approved for other diseases. The mechanisms of action of these molecules are …

Leishmaniasis is a tropical infectious disease caused by the protozoan Leishmania parasite.
The disease is transmitted by female sand flies and, depending on the infecting parasite …

Human leishmaniosis caused by Leishmania infantum is an important health problem
worldwide. One of the main aspects arousing interest is the epidemiological scenario …

Introduction The leishmaniases represent a group of parasitic diseases caused by infection
with one of several species of Leishmania parasites. Disease presentation varies because …

Background Miltefosine treatment failure in visceral leishmaniasis in Brazil has been
associated with deletion of the miltefosine susceptibility locus (MSL) in Leishmania infantum …

Leishmania infantum causes visceral leishmaniasis, a deadly vector-borne disease
introduced to the Americas during the colonial era. This non-native trypanosomatid parasite …