Scleral structure and biomechanics
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …
Optical coherence tomography and glaucoma
A Geevarghese, G Wollstein, H Ishikawa… - Annual review of …, 2021 - annualreviews.org
Early detection and monitoring are critical to the diagnosis and management of glaucoma, a
progressive optic neuropathy that causes irreversible blindness. Optical coherence …
progressive optic neuropathy that causes irreversible blindness. Optical coherence …
Microvascular density in glaucomatous eyes with hemifield visual field defects: an optical coherence tomography angiography study
T Akagi, Y Iida, H Nakanishi, N Terada… - American journal of …, 2016 - Elsevier
Purpose To investigate microcirculation of peripapillary retina and optic disc in eyes with
primary open-angle glaucoma (POAG) and hemifield visual field (VF) defects. Design …
primary open-angle glaucoma (POAG) and hemifield visual field (VF) defects. Design …
Discovery and clinical translation of novel glaucoma biomarkers
Glaucoma and other optic neuropathies are characterized by progressive dysfunction and
loss of retinal ganglion cells and their axons. Given the high prevalence of glaucoma-related …
loss of retinal ganglion cells and their axons. Given the high prevalence of glaucoma-related …
Autoregulation and neurovascular coupling in the optic nerve head
Impairments of autoregulation and neurovascular coupling in the optic nerve head play a
critical role in ocular pathologies, especially glaucomatous optic neuropathy. We critically …
critical role in ocular pathologies, especially glaucomatous optic neuropathy. We critically …
Translating ocular biomechanics into clinical practice: current state and future prospects
Biomechanics is the study of the relationship between forces and function in living
organisms and is thought to play a critical role in a significant number of ophthalmic …
organisms and is thought to play a critical role in a significant number of ophthalmic …
[HTML][HTML] Lamina cribrosa visibility using optical coherence tomography: comparison of devices and effects of image enhancement techniques
Purpose.: To compare the visibility of the lamina cribrosa (LC) in optic disc images acquired
from 60 glaucoma and 60 control subjects using three optical coherence tomography (OCT) …
from 60 glaucoma and 60 control subjects using three optical coherence tomography (OCT) …
[HTML][HTML] Estimating human trabecular meshwork stiffness by numerical modeling and advanced OCT imaging
Purpose: The purpose of this study was to estimate human trabecular meshwork (hTM)
stiffness, thought to be elevated in glaucoma, using a novel indirect approach, and to …
stiffness, thought to be elevated in glaucoma, using a novel indirect approach, and to …
Astrocytes in the optic nerve head of glaucomatous mice display a characteristic reactive phenotype
Purpose: Optic nerve head astrocytes, a subtype of white-matter astrocytes, become reactive
early in the course of glaucoma. It was shown recently that in the DBA/2J mouse model of …
early in the course of glaucoma. It was shown recently that in the DBA/2J mouse model of …
Optical coherence tomography and optical coherence tomography angiography: essential tools for detecting glaucoma and disease progression
Early diagnosis and detection of disease progression are critical to successful therapeutic
intervention in glaucoma, the leading cause of irreversible blindness worldwide. Optical …
intervention in glaucoma, the leading cause of irreversible blindness worldwide. Optical …