Non-coding RNA networks in cancer

E Anastasiadou, LS Jacob, FJ Slack - Nature Reviews Cancer, 2018 - nature.com
Thousands of unique non-coding RNA (ncRNA) sequences exist within cells. Work from the
past decade has altered our perception of ncRNAs from'junk'transcriptional products to …

An emerging class of long non-coding RNA with oncogenic role arises from the snoRNA host genes

AA Zimta, AB Tigu, C Braicu, C Stefan, C Ionescu… - Frontiers in …, 2020 - frontiersin.org
The small nucleolar RNA host genes (SNHGs) are a group of long non-coding RNAs, which
are reported in many studies as being overexpressed in various cancers. With very few …

m6A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1

Y Wu, X Yang, Z Chen, L Tian, G Jiang, F Chen, J Li… - Molecular cancer, 2019 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) have emerged as critical players in
cancer progression, but their functions in colorectal cancer (CRC) metastasis have not been …

SP1-induced lncRNA-ZFAS1 contributes to colorectal cancer progression via the miR-150-5p/VEGFA axis

X Chen, K Zeng, M Xu, X Hu, X Liu, T Xu, B He… - Cell death & …, 2018 - nature.com
Increasing long non-coding RNAs (lncRNAs) have been reported to play key roles in the
development and progression of various malignancies. ZNFX1 antisense RNA1 (ZFAS1) …

[HTML][HTML] LncRNA SNHG6 promotes proliferation, invasion and migration in colorectal cancer cells by activating TGF-β/Smad signaling pathway via targeting UPF1 and …

X Wang, Q Lai, J He, Q Li, J Ding, Z Lan… - … journal of medical …, 2019 - ncbi.nlm.nih.gov
Background: Long noncoding RNAs (lncRNAs) are non-protein coding transcripts longer
than 200 nucleotides in length. They drive many important cancer phenotypes through their …

The human-specific and smooth muscle cell-enriched LncRNA SMILR promotes proliferation by regulating mitotic CENPF mRNA and drives cell-cycle progression …

AD Mahmoud, MD Ballantyne, V Miscianinov… - Circulation …, 2019 - Am Heart Assoc
Rationale: In response to blood vessel wall injury, aberrant proliferation of vascular smooth
muscle cells (SMCs) causes pathological remodeling. However, the controlling mechanisms …

Long non-coding RNAs: key regulators of epithelial-mesenchymal transition, tumour drug resistance and cancer stem cells

R Heery, SP Finn, S Cuffe, SG Gray - Cancers, 2017 - mdpi.com
Epithelial mesenchymal transition (EMT), the adoption by epithelial cells of a mesenchymal-
like phenotype, is a process co-opted by carcinoma cells in order to initiate invasion and …

Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking

P Kaewsapsak, DM Shechner, W Mallard, JL Rinn… - Elife, 2017 - elifesciences.org
The spatial organization of RNA within cells is a crucial factor influencing a wide range of
biological functions throughout all kingdoms of life. However, a general understanding of …

Long non-coding RNA RP11-468E2. 5 curtails colorectal cancer cell proliferation and stimulates apoptosis via the JAK/STAT signaling pathway by targeting STAT5 …

L Jiang, XH Zhao, YL Mao, JF Wang, HJ Zheng… - Journal of Experimental …, 2019 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are tumor-associated biological
molecules and have been found to be implicated in the progression of colorectal cancer …

Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer

Z Liu, Z Chen, R Fan, B Jiang, X Chen, Q Chen, F Nie… - Molecular cancer, 2017 - Springer
Abstract Background Long noncoding RNAs (lncRNAs) have emerged as critical regulators
in a variety of human cancers, including gastric cancer (GC). However, the function and …