The role of extracellular vesicles in COVID-19 virus infection

M Hassanpour, J Rezaie, M Nouri, Y Panahi - Infection, Genetics and …, 2020 - Elsevier
Extracellular vesicles releasing from various types of cells contribute to intercellular
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …

[HTML][HTML] Viral membrane fusion

SC Harrison - Virology, 2015 - Elsevier
Membrane fusion is an essential step when enveloped viruses enter cells. Lipid bilayer
fusion requires catalysis to overcome a high kinetic barrier; viral fusion proteins are the …

SARS-CoV-2 requires acidic pH to infect cells

AJB Kreutzberger, A Sanyal… - Proceedings of the …, 2022 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cell entry starts with
membrane attachment and ends with spike (S) protein–catalyzed membrane fusion …

Influenza hemagglutinin and neuraminidase: Yin–Yang proteins coevolving to thwart immunity

I Kosik, JW Yewdell - Viruses, 2019 - mdpi.com
Influenza A virions possess two surface glycoproteins—the hemagglutinin (HA) and
neuraminidase (NA)—which exert opposite functions. HA attaches virions to cells by binding …

Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane

Y Ge, X Shi, S Boopathy, J McDonald, AW Smith… - elife, 2020 - elifesciences.org
Mitochondrial membrane dynamics is a cellular rheostat that relates metabolic function and
organelle morphology. Using an in vitro reconstitution system, we describe a mechanism for …

IFITMs restrict the replication of multiple pathogenic viruses

JM Perreira, CR Chin, EM Feeley, AL Brass - Journal of molecular biology, 2013 - Elsevier
The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of
pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and …

Diverse effects of exosomes on COVID-19: a perspective of progress from transmission to therapeutic developments

S Gurunathan, MH Kang, JH Kim - Frontiers in Immunology, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new strain of
coronavirus and the causative agent of the current global pandemic of coronavirus disease …

Direct visualization of the conformational dynamics of single influenza hemagglutinin trimers

DK Das, R Govindan, I Nikić-Spiegel, F Krammer… - Cell, 2018 - cell.com
Influenza hemagglutinin (HA) is the canonical type I viral envelope glycoprotein and
provides a template for the membrane-fusion mechanisms of numerous viruses. The current …

Virus and cell fusion mechanisms

B Podbilewicz - Annual review of cell and developmental …, 2014 - annualreviews.org
In biomembrane fusion pathways, membranes are destabilized through insertions of
amphipathic protein segments, lipid reorganization via hemifusion, protein restructuring, and …

The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases

JT Earnest, MP Hantak, K Li, PB McCray Jr… - PLoS …, 2017 - journals.plos.org
Infection by enveloped coronaviruses (CoVs) initiates with viral spike (S) proteins binding to
cellular receptors, and is followed by proteolytic cleavage of receptor-bound S proteins …