Abstract The VARC (Valve Academic Research Consortium) for transcatheter aortic valve
replacement set the standard for selecting appropriate clinical endpoints reflecting safety …

Paravalvular leak (PVL) is a serious complication after surgical valve replacement or after
transcatheter aortic valve replacement. Approximately 1–5% of PVLs can lead to serious …

Purpose of review As the number of surgical and transcatheter valve replacements continue
to increase in the aging population, so does the incidence of paravalvular leak (PVL). Given …

Paravalvular leak (PVL) is a complication that occurs in 5–17% of patients after surgical
prosthetic valve implantation. Whereas PVLs can be benign, some PVLs are associated with …

Mitral paravalvular leaks (PVLs) commonly occur in patients with prosthetic valves.
Paravalvular defects may be clinically inconsequential and may aggravate hemolysis or …

Paravalvular leak incidence after mitral surgical replacement ranges from 7% to 17%.
Between 1% and 5% of these are clinically significant. Large PVLs can cause important …

Background Mitral paravalvular leaks (mPVL) are a recognized complication for patients
with mitral valve prostheses. Although clinically insignificant for many patients, it may pose …

In recent years, computational fluid dynamics (CFD) has been extensively used in
biomedical research on heart diseases due to its non-invasiveness and relative ease of use …

Objective: Clinical presentation of patients with mitral paravalvular leakage (PVL) varies
from asymptomatic to heart failure related with hemolytic anemia or pulmonary hypertension …

Background The clinical significance of pannus in the prosthetic mitral valve (MV) is not well
documented. Objectives To investigate the clinical significance of pannus on cardiac …